ZJY-54
ZJY-54 is an orally active dual-target inhibitor of EGFR/LSD1, with IC50 values of 3.8 nM and 0.6 μM, respectively. ZJY-54 can inhibit the proliferation of non-small cell lung cancer cells, induce the accumulation of H3K4me2 and H3K9me2, and inhibit the phosphorylation of the EGFR signaling pathway. ZJY-54 has anti-tumor activity.
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- CAS No.: 3091379-82-4
- Formule: C29H30D3N7O2
- Masse moléculaire:514.64
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 3091379-82-4
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Unlabeled CAS 1421373-68-3
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Masse moléculaire 514.64
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Formule C29H30D3N7O2
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SMILES
COC1=C(C=C(C(N2C[C@@H](CC2)N(C)C)=C1)NC(C=C)=O)NC3=NC(C4=CN(C([2H])([2H])[2H])C5=CC=CC=C54)=CC=N3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZJY-54 Related Classifications
HY-168968S Related Classifications
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