12 Results for "

Leukotriene E4

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "Leukotriene E4" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-113465
CAS No.: 75715-89-8
Purity:  99.80%
Synonyms: LTE4
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma.
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Cat. No.: HY-113465S
CAS No.: 1240398-14-4
Synonyms: LTE4-d5
Leukotriene E4-d5 (LTE4-d5) is the d-5-labeled Leukotriene E4 (HY-113465). Leukotriene E4 is a stable final metabolite of cysteinyl leukotrienes, produced by immune cells such as mast cells and eosinophils. Leukotriene E4 serves as a key biomarker for evaluating asthma severity, Aspirin (HY-14654) sensitivity, and mast cell activation disorders. Leukotriene E4 is a full functional agonist of CysLT1R, which induces sustained intracellular calcium mobilization and Erk phosphorylation. Leukotriene E4 mediates inflammation in a P2Y12 receptor-dependent manner. Leukotriene E4 can be used in the research of asthma and non-steroidal anti-inflammatory drug-exacerbated respiratory diseases .
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Cat. No.: HY-W747567
CAS No.: 89461-65-4
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Leukotriene E4 methyl ester is a methyl ester of Leukotriene E4 (HY-113465). Leukotriene E4 methyl ester can be used for the research of inflammatory diseases .
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Cat. No.: HY-156978
CAS No.: 111974-60-8
Purity:  99.92%
Synonyms: Wy-48252
Target:  

Leukotriene Receptor

Research Areas:  

Others

Ritolukast (Wy-48252) is an orally active aerosol leukotriene (LTD4/E4) receptor antagonist. Ritolukast can be used to inhibit the bronchoconstriction caused by aerosol LTD4 in guinea pigs, with an ID50 of 0.5mg/kg .
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Cat. No.: HY-111212
CAS No.: 88107-10-2
Purity:  ≥99.0%
Synonyms: LY171883
Target:  

Leukotriene Receptor

Research Areas:  

Inflammation/Immunology

Tomelukast (LY171883) is an orally active leukotriene D4 and E4 antagonist. Tomelukast can be used for the research of asthma .
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Cat. No.: HY-130440
CAS No.: 83851-42-7
Leukotriene F4 (LTF4), is a lipid that belongs to the Cysteinyl Leukotriene (CysTL) family . Leukotriene F4 induces bronchoconstriction with an ED50 of 16 μg/kg . The precursor of LTF4 is Leukotriene E4 (LTE4), which isformed from the action of a glutamyl transferase .
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Cat. No.: HY-113465A
CAS No.: 75715-88-7
11-trans Leukotriene E4 is an isomer of Leukotriene E4 (LTE4). Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 is equipotent to LTE4 in contracting guinea pig ileum .
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Cat. No.: HY-131395
CAS No.: 80115-95-3
Synonyms: N-Acetyl-LTE4
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

N-Acetyl-Leukotriene E4 (N-Acetyl-LTE4) is a metabolite of Leukotriene E4 (LTE4) (HY-113465), which is detected in bile and urine . N-Acetyl-Leukotriene E4 produces a vasoconstriction in the mesenteric vessels which led to reduction of blood flow to the gut .
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Cat. No.: HY-107610
CAS No.: 146662-42-2
Purity:  99.60%
Target:  

Leukotriene Receptor

Research Areas:  

Inflammation/Immunology

SR2640 (hydrochloride) is a potent and selective competitive leukotriene D4/leukotriene E4 antagonist. SR2640 can be used for researching the role of leukotrienes in human asthma .
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Cat. No.: HY-123575
CAS No.: 127345-02-2
Target:  

Leukotriene Receptor

Research Areas:  

Inflammation/Immunology

LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC50s of 4 μM .
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Cat. No.: HY-113758
CAS No.: 97581-70-9
Target:  

Leukotriene Receptor

Research Areas:  

Inflammation/Immunology

LY 163443 is a selective antagonist of leukotrienes D4 (LTD4) and E4 (LTE4). LY 163443 can antagonize LTD4-induced contractions of guinea pig ileum, trachea, and lung parenchyma. LY 163443 also inhibits tracheal contractions to LTE4 .
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Cat. No.: HY-107610R
CAS No.: 146662-42-2
SR2640 hydrochloride (Standard) is the analytical standard of SR2640 (hydrochloride) (HY-107610). This product is intended for research and analytical applications. SR2640 (hydrochloride) is a potent and selective competitive leukotriene D4/leukotriene E4 antagonist. SR2640 can be used for researching the role of leukotrienes in human asthma .
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