1 Result for "

Lin28-let-7 complex

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Lin28-let-7 complex" in MCE Product Catalog:

Art. -Nr.: HY-177733
Forschungsgebiete:  

Cancer

MG-Lin3 is a Lin28 molecular glue degrader. MG-Lin3 recruits the E3 ubiquitin ligase RNF126 to form a ternary complex, induces the degradation of Lin28 via the ubiquitin-proteasome pathway, and restores the levels of mature let-7 miRNA. MG-Lin3 can be used in research on ovarian cancer, ovarian teratocarcinoma, and uterine cancer .
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