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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Lysosomal α-Glucosidase
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Lysosomal α-Glucosidase" in MCE Product Catalog:
Cat. No.: HY-E70183
Synonyms: EC:3.2.1.20; GAA
Cat. No.: HY-108828
CAS No.: 420784-05-0
Synonyms: rhGAA
Target:
Research Areas:
Alglucosidase alfa (rhGAA) is a recombinant human acid α-glucosidase. Alglucosidase alfa is taken up by cells via the cation-independent mannose-6-phosphate receptor (CI-MPR) pathway and transported to lysosomes, where GAA degrades glycogen in the acidic lysosomal environment. Alglucosidase alfa is applicable to research related to lysosomal glycogen metabolism and glycogen storage diseases .
Cat. No.: HY-154995
CAS No.: 3033570-20-3
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Research Areas:
N-4′-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) is an agonit of lysosomal acid α-glucosidase (GAA). N-4′-(p-Trifluoromethylphenyl)butyl-DAB increases intracellular GAA activities dose-dependently, in Pompe patient's fibroblasts with the M519V mutation .
Cat. No.: HY-184340
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α-Glucosidase-IN-118 is a non-competitive inhibitor of α-glucosidase with a IC50 of 2.77 μM, and it shows no inhibitory activity against β-glucosidase. α-Glucosidase-IN-118 binds to the entrance of the α-glucosidase active site to block substrate release. α-Glucosidase-IN-118 can be used in the research of diabetes, obesity and lysosomal storage diseases .
Cat. No.: HY-P99803
CAS No.: 2145123-44-8
Synonyms: VAL-1221
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Research Areas:
Cat. No.: HY-P810401
Synonyms: 70 kDa Lysosomal alpha-Glucosidase, Acid alpha Glucosidase, Acid maltase, AGlucosidase alfa, Alpha Glucosidase, GAA, Glucosidase alpha acid (Pompe disease glycogen storage disease type II), Glucosidase alpha acid, Glucosidase alpha, LYAG
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
