1 Result for "

Methoxyamine hydrochloride (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Methoxyamine hydrochloride (Standard)" in MCE Product Catalog:

Cat. No.: HY-Y0958R
CAS No.: 593-56-6
Synonyms: O-Methylhydroxylamine hydrochloride (Standard)
Research Areas:  

Cancer

Methoxyamine hydrochloride (Standard) is the analytical standard of Methoxyamine hydrochloride. This product is intended for research and analytical applications. Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents .
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