1 Result for "

N-Myc-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "N-Myc-IN-1" in MCE Product Catalog:

Cat. No.: HY-186247
CAS No.: 885986-52-7
Target:  

c-Myc Apoptosis

Research Areas:  

Neurological Disease Cancer

N-Myc-IN-1 is a selective N-Myc inhibitor/degrader with a Kd value of 1.47 μM. N-Myc-IN-1 promotes phosphorylation of N-Myc at threonine-58, triggers N-Myc degradation via the ubiquitin-proteasome pathway, and suppresses the expression of N-Myc target genes. N-Myc-IN-1 reduces the viability of MYCN-dependent tumor cells and induces apoptosis. N-Myc-IN-1 can be used in the research of neuroblastoma [1].
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