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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
NMDA agonist-1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "NMDA agonist-1" in MCE Product Catalog:
Cat. No.: HY-169950
CAS No.: 2576586-47-3
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NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a Ki value of 96 nM. NMDA agonist 1 acts as a partial agonist of the GluN1/GluN2B complex with an EC50 value of 78 nM .
Synonyms: Norclozapine; Desmethylclozapine; Normethylclozapine
Research Areas:
N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist .
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GP130 receptor agonist-1 is a potent, brain-penetrant and orally active GP130 receptor agonist. GP130 receptor agonist-1 has a neuroprotective effect on NMDA-induced neurotoxicity .
Synonyms: NRX-1074; AGN-241660
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Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist .
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S1R agonist 1 (Compound 6b) is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. S1R agonist 1 exhibits neuroprotection against ROS and NMDA-induced neurotoxicity .
Cat. No.: HY-G0021S1
CAS No.: 2705402-91-9
Synonyms: Norclozapine-d8 hydrochloride; Desmethylclozapine-d8 hydrochloride; Normethylclozapine-d8 hydrochloride
Cat. No.: HY-G0021S
CAS No.: 1189888-77-4
Synonyms: Norclozapine-d8; Desmethylclozapine-d8; Normethylclozapine-d8
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S1R agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. S1R agonist 1 hydrochloride exhibits neuroprotection against ROS and NMDA-induced neurotoxicity .
Synonyms: Norclozapine (Standard); Desmethylclozapine (Standard); Normethylclozapine (Standard)
Research Areas:
N-Desmethylclozapine (Standard) is the analytical standard of N-Desmethylclozapine. This product is intended for research and analytical applications. N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist .
Synonyms: D,L-(tetrazol-5-yl)glycine; LY 285265
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(RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is a highly potent and selective N-methyl-D-aspartate (NMDA) receptor agonist . (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D and GluN1/GluN2A, respectively . (RS)-(Tetrazol-5-yl)glycine induces seizure responses and Fos in mice .
Cat. No.: HY-102053R
CAS No.: 1421866-48-9
Synonyms: NRX-1074 (Standard); AGN-241660 (Standard)
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Apimostinel (Standard) is the analytical standard of Apimostinel (HY-102053). This product is intended for research and analytical applications. Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
