1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR
  3. Apimostinel

Apimostinel (Synonyms: NRX-1074; AGN-241660)

Cat. No.: HY-102053 Purity: 99.04%
Handling Instructions

Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist.

For research use only. We do not sell to patients.

Apimostinel Chemical Structure

Apimostinel Chemical Structure

CAS No. : 1421866-48-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 720 In-stock
Estimated Time of Arrival: December 31
5 mg USD 650 In-stock
Estimated Time of Arrival: December 31
10 mg USD 950 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist.

In Vitro

Apimostinel (NRX-1074) modulates the NMDA receptor in a similar fashion to GLYX-13, but has a synthetic modification to one of the amino acids, conferring increased potency and oral bioavailability[1].

In Vivo

In preclinical models the two compounds both appear to be highly efficacious across a number of CNS disorders[1].

Clinical Trial
Molecular Weight

503.59

Formula

C₂₅H₃₇N₅O₆

CAS No.

1421866-48-9

SMILES

C[[email protected]@H](O)[[email protected]@H](C(N)=O)NC([[email protected]@]1(CC2=CC=CC=C2)N(C([[email protected]]3N(C([[email protected]]([[email protected]](O)C)N)=O)CCC3)=O)CCC1)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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