1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR

Apimostinel (Synonyms: NRX-1074; AGN-241660)

Cat. No.: HY-102053
Handling Instructions

Apimostinel is an oral NMDA receptor partial agonist.

For research use only. We do not sell to patients.

Apimostinel Chemical Structure

Apimostinel Chemical Structure

CAS No. : 1421866-48-9

Size Stock
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Apimostinel is an oral NMDA receptor partial agonist.

In Vitro

Apimostinel (NRX-1074) modulates the NMDA receptor in a similar fashion to GLYX-13, but has a synthetic modification to one of the amino acids, conferring increased potency and oral bioavailability[1].

In Vivo

In preclinical models the two compounds both appear to be highly efficacious across a number of CNS disorders[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9857 mL 9.9287 mL 19.8574 mL
5 mM 0.3971 mL 1.9857 mL 3.9715 mL
10 mM 0.1986 mL 0.9929 mL 1.9857 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

503.59

Formula

C₂₅H₃₇N₅O₆

CAS No.

1421866-48-9

SMILES

C[[email protected]@H](O)[[email protected]@H](C(N)=O)NC([[email protected]@]1(CC2=CC=CC=C2)N(C([[email protected]]3N(C([[email protected]]([[email protected]](O)C)N)=O)CCC3)=O)CCC1)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Apimostinel
Cat. No.:
HY-102053
Quantity:

Apimostinel

Cat. No.: HY-102053