1 Result for "

Necturus maculosus

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Necturus maculosus" in MCE Product Catalog:

Cat. No.: HY-182386
CAS No.: 13422-16-7
Target:  

NKCC

Research Areas:  

Metabolic Disease Endocrinology

Triflocin is an orally active diuretic and Na +-K +-2Cl cotransporter inhibitor with an IC50 of 3×10 -5 M. Triflocin inhibits the outward basolateral electrogenic Na-(HCO3) n>1 cotransport in the proximal tubule. Triflocin has no tendency to induce hyperglycemia, and its blood glucose-elevating effect is extremely weak, such that an increase in blood glucose levels can only be detected under special conditions such as glucose loading. Triflocin is more prone to induce hypoglycemia .
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