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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
Neural progenitor cells
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "Neural progenitor cells" in MCE Product Catalog:
15
15 Publications Verification
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DMH-1 is a selective BMP inhibitor. DMH-1 upregulates the expression of SOX1. DMH-1 increases cardiomyocyte progenitor cells and promotes the differentiation of mouse embryonic stem cells into cardiomyocytes. DMH-1 induces the differentiation of hiPSC-derived neural progenitor cells into β3-tubulin-positive neurons .
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6 Cited Publications
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Carboxy pyridostatin trifluoroacetate salt is a G-quadruplex ligand. Carboxy pyridostatin trifluoroacetate salt has a highly molecular specificity to RNA on DNA G4s and reduces ATF-5 protein. Carboxy pyridostatin trifluoroacetate salt reduces cell proliferation and hinders stress granule (SG) formation .
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6 Cited Publications
Cat. No.: HY-112680
CAS No.: 1417638-60-8
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Carboxypyridostatin is a G-quadruplex ligand. Carboxypyridostatin has a highly molecular specificity to RNA on DNA G4s and reduces ATF-5 protein. Carboxypyridostatin reduces cell proliferation and hinders stress granule (SG) formation .
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2 Cited Publications
INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC50s of 0.24 μM and 0.23 μM, respectively. INDY binds in the ATP pocket of the enzyme and has a Ki value of 0.18 μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells .
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1 Cited Publications
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SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells.
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1 Cited Publications
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Neuropathiazol, a neuronal differentiation inducer, selectively induces neuronal differentiation of multipotent hippocampal neural progenitor cells .
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1 Cited Publications
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Cat. No.: HY-W018555
CAS No.: 921-01-7
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Cat. No.: HY-12273G
CAS No.: 1206711-16-1
Cat. No.: HY-N10631
CAS No.: 70858-45-6
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Paucimannose is a mannosidic N-glycan epitope. It acts as a carcinoembryonic antigen, and a marker for cancer, stem cell properties and inflammation. Paucimannose mainly exists in plants and invertebrates. It consists of oligomannose-type N-glycans that preferentially bind to mannose-binding lectin. Paucimannose localizes on the surface of resting cells and translocates upon cell activation. It can be used in studies related to Pseudomonas aeruginosa infection, cancer and pancreatitis .
Cat. No.: HY-178048
CAS No.: 3086460-35-4
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Neuroprotective agent 13 is a brain-penetrant 1H-benzo[d]imidazoles compound with neuroprotective effect. Neuroprotective agent 13 can activate autophagy and clear SCMAS accumulation from iPSC-derived neural progenitor cells. Neuroprotective agent 13 can be used for the research of neurological disease, such as neuronal ceroid lipofuscinoses (NCLs) .
Cat. No.: HY-10396A
CAS No.: 409369-54-6
Synonyms: (2R,3S)-PF 03491390; (2R,3S)-IDN-6556
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(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan (HY-10396). Emricasan is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV)-induced increases in caspase-3 activity and protected human cortical neural progenitors .
Cat. No.: HY-10996
CAS No.: 1262770-73-9
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KHS101 is a blood-brain barrier-penetrant anticancer agent that primarily functions by inhibiting HSPD1 (IC50 = 14.4 μM) and TACC3 across different cellular backgrounds. KHS101 promotes the aggregation of HSPD1 with client proteins, destabilizes TACC3, and reduces the levels of TACC3, Aurora A and PLK1. KHS101 induces autophagy, apoptosis, cell cycle exit and neuronal differentiation; it suppresses cancer cell growth, motility, EMT and stemness; it also impairs mitochondrial bioenergetics and glycolysis in glioblastoma cells. KHS101 can be used in research related to glioblastoma multiforme and breast cancer .
Cat. No.: HY-178052
CAS No.: 3086460-57-0
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Neuroprotective agent 14 is a brain-penetrant 1H-benzo[d]imidazoles compound with neuroprotective effect. Neuroprotective agent 14 can activate autophagy and clear SCMAS accumulation from iPSC-derived neural progenitor cells. Neuroprotective agent 14 can be used for the research of neurological disease, such as neuronal ceroid lipofuscinoses (NCLs) .
Cat. No.: HY-W018555R
CAS No.: 921-01-7
Cat. No.: HY-174987
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mGluR1 activator-1 is a stable Vitamin K (HY-B2172) analogue and a mGluR1 activator that can penetrate the blood-brain barrier. mGluR1 activator-1 exhibits strong transcriptional activation via steroid and xenobiotic receptor as well as retinoic acid receptor. mGluR1 activator-1 induces neuronal differentiation in mouse neural progenitor cells. mGluR1 activator-1 can be used for the study of neurodegenerative disease such as Alzheimer’s .
Cat. No.: HY-D3179
CAS No.: 1451048-96-6
Cat. No.: HY-10591R
CAS No.: 880090-88-0
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Neuropathiazol (Standard) is the analytical standard of Neuropathiazol (HY-10591). This product is intended for research and analytical applications. Neuropathiazol, a neuronal differentiation inducer, selectively induces neuronal differentiation of multipotent hippocampal neural progenitor cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
