14 Results for "

Nitroimidazole derivatives

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Nitroimidazole derivatives" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-B0508
CAS No.: 16773-42-5
Synonyms: Ro 7-0207
Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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Cat. No.: HY-121657
CAS No.: 62580-80-7
Purity:  99.24%
Synonyms: Ro 11-2616
Target:  

Parasite Bacterial

Research Areas:  

Others

Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.
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Cat. No.: HY-B0508S1
Synonyms: Ro 7-0207-13C2,15N2
Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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Cat. No.: HY-119480
CAS No.: 19622-55-0
Purity:  99.20%
Target:  

Bacterial

Research Areas:  

Infection

Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
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Cat. No.: HY-121648
CAS No.: 140448-29-9
Research Areas:  

Cancer

PK 130 is a 2-nitroimidazole derivative that has radiosensitizing effects on hypoxic cells. PK 130 increases the radiosensitivity of Chinese hamster V79 cells under hypoxic conditions .
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Cat. No.: HY-107030R
CAS No.: 21721-92-6
Synonyms: EMD-15700 (Standard)
Nitrefazole (Standard) is the analytical standard of Nitrefazole. This product is intended for research and analytical applications. Nitrefazole is a 4-nitroimidazole derivative with strong and long lasting inhibition of aldehyde dehydrogenase (ALDH), an enzyme involved in the metabolism of alcohol.
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Cat. No.: HY-121657R
CAS No.: 62580-80-7
Synonyms: Ro 11-2616 (Standard)
Research Areas:  

Others

Ornidazole diol (Standard) is an analytical standard for Ornidazole diol. This product is used for research and analytical applications. Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.
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Cat. No.: HY-122288
CAS No.: 64444-68-4
Target:  

Bacterial

Research Areas:  

Infection

SC 28538 is a compound with antimicrobial activity. SC 28538 exerts its antimicrobial effect by reducing its nitro moiety in an anaerobic environment to form cytotoxic free radicals that can damage DNA and other key biomolecules of microorganisms .
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Cat. No.: HY-B0508S
CAS No.: 2747915-64-4
Synonyms: Ro 7-0207-d5
Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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Cat. No.: HY-B0508R
CAS No.: 16773-42-5
Synonyms: Ro 7-0207 (Standard)
Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
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Cat. No.: HY-119480R
CAS No.: 19622-55-0
Target:  

Bacterial

Research Areas:  

Infection

Megazol (Standard) is the analytical standard of Megazol. This product is intended for research and analytical applications. Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
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Cat. No.: HY-W018143
CAS No.: 3034-41-1
Target:  

Bacterial Fungal

Research Areas:  

Infection

1-Methyl-4-nitroimidazole is an antibacterial agent. 1-Methyl-4-nitroimidazole is reduced by bacterial nitroreductases to form toxic derivatives, which cause DNA damage, inhibit bacterial nucleic acid synthesis, generate toxic superoxides through futile cycling of reduced radical anions, and induce bacterial cell death. 1-Methyl-4-nitroimidazole exhibits moderate in vitro activity against bacteria and fungal. 1-Methyl-4-nitroimidazole can be used in the research of skin infections, purulent infections and urinary tract infections .
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Cat. No.: HY-189049
CAS No.: 1214752-97-2
Target:  

Parasite

Research Areas:  

Infection

Antiparasitic agent-47 is a nitroimidazole derivative with potent antiparasitic activity. Antiparasitic agent-47 exhibits IC50 values of 0.72 μM and 9.33 μM against sensitive and drug-resistant strains of Trichomonas vaginalis, respectively. Antiparasitic agent-47 can be used in research related to trichomoniasis .
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Cat. No.: HY-180543
CAS No.: 3049284-12-7
Target:  

HIV

Research Areas:  

Infection

HIV-IN-13 prodrug (Compound 8) is a prodrug of an HIV inhibitor. Without the addition of glutathione (GSH), the HIV-IN-13 prodrug has no antiviral activity, but when 1 mM and 2 mM GSH are added, the EC50 values for HIV-1 are 10 μM and 8.2 μM respectively. HIV-IN-13 prodrug can be used in HIV infection research .
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