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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
O. melastigma
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "O. melastigma" in MCE Product Catalog:
Cat. No.: HY-W041308
CAS No.: 64359-81-5
Synonyms: Kathon 930
Research Areas:
DCOIT (Kathon 930) is an isothiazolinone biocide and environmental pollutant that directly binds to G protein α subunits, with KD values of 0.92 mM and 0.4 mM for Gαs and Gαi, respectively. Binding of DCOIT to Gαi enhances the interaction between Gαi and mitochondrial calcium uniporter (MCU), alters the subcellular distribution of intracellular Ca 2+, and activates PKC/MEK/ERK signaling. DCOIT upregulates CYP19a transcription and aromatase activity, thereby disrupting steroid hormone homeostasis. DCOIT is used in studies of reproductive endocrine disruption and environmental toxicology .
Cat. No.: HY-W041308R
CAS No.: 64359-81-5
Synonyms: Kathon 930 (Standard)
Research Areas:
DCOIT (Standard) (Kathon 930 (Standard)) is the analytical standard of DCOIT (HY-W041308). This product is intended for research and analytical applications. DCOIT (Kathon 930) is an isothiazolinone biocide and environmental pollutant that directly binds to G protein α subunits, with KD values of 0.92 mM and 0.4 mM for Gαs and Gαi, respectively. Binding of DCOIT to Gαi enhances the interaction between Gαi and mitochondrial calcium uniporter (MCU), alters the subcellular distribution of intracellular Ca 2+, and activates PKC/MEK/ERK signaling. DCOIT upregulates CYP19a transcription and aromatase activity, thereby disrupting steroid hormone homeostasis. DCOIT is used in studies of reproductive endocrine disruption and environmental toxicology .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
