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Oroxylin A-7-O-glucuronide

" in MedChemExpress (MCE) Product Catalog:

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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-N2481
    Oroxylin A-7-O-glucuronide
    1 Publications Verification

    Oroxyloside; Oroxylin A-7-O-β-D-glucuronide

    Prolyl Endopeptidase (PREP) Drug Metabolite JNK PPAR NF-κB Interleukin Related Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .
    Oroxylin A-7-O-glucuronide
  • HY-N2481R

    Oroxyloside (Standard); Oroxylin A-7-O-β-D-glucuronide (Standard)

    Reference Standards Prolyl Endopeptidase (PREP) Drug Metabolite JNK PPAR NF-κB Interleukin Related Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Oroxylin A-7-O-glucuronide (Standard) is the analytical standard of Oroxylin A-7-O-glucuronide (HY-N2481). This product is intended for research and analytical applications. Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .
    Oroxylin A-7-O-glucuronide (Standard)

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