182 Results for "

PNA

" in MedChemExpress (MCE) Product Catalog:
Products (182)

182 Results for "PNA" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P2573
CAS No.: 70967-97-4
Synonyms: Suc-Ala-Ala-Pro-Phe-PNA
Target:  

Peptides

Research Areas:  

Others

Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils .
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1
1 Cited Publications
Cat. No.: HY-P4476
CAS No.: 72682-69-0
Target:  

Ser/Thr Protease

Research Areas:  

Others

Suc-AAPA-pNA is a substrate for chymotrypsin A and elastase. Suc-AAPA-pNA can be used for enzyme activity assay .
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1
1 Cited Publications
Cat. No.: HY-P3443
Synonyms: PNA
Peanut agglutinin (PNA) is a carbohydrate-recognition protein that binds competitively and irreversibly to cell-surface β-D-Gal (1-3)-GalNAc, and this binding can be inhibited by D-galactose and asialofetuin. Peanut agglutinin recognizes exposed glycoepitopes and reflects the glycosylation status of cells. Peanut agglutinin can label glycoconjugates at neuromuscular junctions to safely visualize synaptic structures. Peanut agglutinin can be used to synthesize dyes to distinguish between normal and tumor tissues. Peanut agglutinin provides support for research on leukemia, Burkitt's tumors, and cutaneous squamous lesions .
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1
1 Cited Publications
Cat. No.: HY-NP0182
Synonyms: PNA (Biotinylated)
Peanut Agglutinin (PNA) Biotinylated is a biotinylated lectin that specifically recognizes and binds to the Galβ1-3GalNAc sequence, thereby targeting SPESP1 and TF blood group antigens. As an acrosome-specific marker, Peanut Agglutinin Biotinylated stains mouse spermatocytes and sperm acrosomes with high specificity, and this binding depends not only on SPESP1 but also recognizes other testicular acrosomal glycoproteins. Peanut Agglutinin Biotinylated accurately identifies TF antigens in Reed-Sternberg cells, histiocytosis X cells, and esophageal squamous cell carcinoma, without cross-reacting with non-specific cells. Peanut Agglutinin Biotinylated maintains staining stability in both B-5 and formalin fixatives, and serves as an important tool for the study of Hodgkin's disease, histiocytosis X, and various malignant tumors .
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1
1 Cited Publications
Cat. No.: HY-P1006
CAS No.: 189950-66-1
Target:  

Caspase

Research Areas:  

Others

Ac-DEVD-pNA is a ligand for caspase-3/-7 and related cysteine proteases .
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1
1 Cited Publications
Cat. No.: HY-P4490
CAS No.: 95632-46-5
Research Areas:  

Others

Suc-Ala-Pro-pNA is a peptide that serves as a substrate to detect the activity and stability of prolyl endopeptidase (PEP) .
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1
1 Cited Publications
Cat. No.: HY-123275
CAS No.: 64815-81-2
Synonyms: S-2238
Target:  

Fluorescent Dye

Research Areas:  

Others

H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
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1
1 Cited Publications
Cat. No.: HY-123275A
CAS No.: 160192-34-7
Purity:  99.40%
Synonyms: S-2238 hydrochloride
Target:  

Fluorescent Dye

Research Areas:  

Others

H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
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1
1 Cited Publications
Cat. No.: HY-123275B
CAS No.: 115388-96-0
Purity:  98.90%
Synonyms: S-2238 acetate
Target:  

Fluorescent Dye

Research Areas:  

Others

H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
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1
1 Cited Publications
Cat. No.: HY-P0021A
CAS No.: 108963-70-8
Synonyms: Spectrozyme PCa; Chromozym Pca diacetate
Target:  

Fluorescent Dye

Research Areas:  

Others

D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .
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1
1 Cited Publications
Cat. No.: HY-W016288
CAS No.: 7149-49-7
Synonyms: 2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde
Target:  

Fungal

Research Areas:  

Infection

Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .
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Cat. No.: HY-119244
CAS No.: 103213-34-9
Purity:  99.92%
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

Gly-Pro-pNA hydrochloride is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA hydrochloride can be investigated as an experimental antidiabetic agent .
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Cat. No.: HY-131409
CAS No.: 62354-43-2
Purity:  99.55%
Synonyms: D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-PNA dihydrochloride; S 2251 dihydrochloride
Target:  

Fluorescent Dye

Research Areas:  

Others

D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .
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Cat. No.: HY-P4202
CAS No.: 128802-76-6
Synonyms: Suc-AEPF-PNA
Research Areas:  

Others

Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidyl-prolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA is used to evaluate the inhibitory effect of target compounds on Pin1, the catalytic activity of Pin1, and other related assays .
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Cat. No.: HY-P4581
CAS No.: 128802-78-8
Synonyms: Suc-ALPF-PNA
Target:  

FKBP

Research Areas:  

Others

Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA) is a synthetic polypeptide substrate that targets FK506-binding protein (FKBP). Suc-Ala-Leu-Pro-Phe-pNA can be used to determine peptidyl-prolyl cis-trans isomerase activity via the chymotrypsin-coupled assay. Suc-Ala-Leu-Pro-Phe-pNA serves as a substrate for human FK506-binding protein hFKBP-12 in the chymotrypsin-FKBP coupled PPIase assay. Suc-Ala-Leu-Pro-Phe-pNA is applicable for the detection and research of PPIase activity .
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Cat. No.: HY-114150D
CAS No.: 162303-66-4
Purity:  99.75%
Target:  

Kallikrein

Research Areas:  

Others

D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
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Cat. No.: HY-137409
CAS No.: 52299-14-6
Target:  

Peptides

Research Areas:  

Others

Suc-AAA-pNA is a hydrolyzable peptide substrate. Suc-AAA-pNA serves as a chromogenic substrate for porcine pancreatic elastase, and undergoes hydrolysis via a virtual transition state with a minor physical step and a dominant chemical step, thereby forming a stable reactant state .
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Cat. No.: HY-P5348
CAS No.: 921771-40-6
Target:  

Peptides

Research Areas:  

Others

Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.)
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Cat. No.: HY-P4460
CAS No.: 60354-61-2
Target:  

Ser/Thr Protease

Research Areas:  

Cancer

AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
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Cat. No.: HY-P2091
CAS No.: 149231-66-3
Target:  

Caspase

Research Areas:  

Inflammation/Immunology

Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes .
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