2 Results for "

PROTAC NSD2 degrader-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PROTAC NSD2 degrader-1" in MCE Product Catalog:

Cat. No.: HY-184968
CAS No.: 3108071-48-0
Domaines de recherche:  

Cancer

PROTAC NSD2 degrader-1 is a PROTAC degrader that selectively targets NSD2, with a DC50 of 0.37 μM. PROTAC NSD2 degrader-1 induces selective degradation of long and short isoforms of NSD2 containing the PWWP1 domain by forming a ternary complex with FBXO22. NSD2 degradation mediated by PROTAC NSD2 degrader-1 depends on the ubiquitin-proteasome system and the neddylation pathway. PROTAC NSD2 degrader-1 can be used in cancer-related research such as non-small cell lung cancer, multiple myeloma and prostate cancer .
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Cat. No.: HY-161575
NSD2 ligand 1 is a NSD2 ligand. NSD2 ligand 1 can be used for synthesis of LLC0424 (HY-161574) (a PROTAC NSD2 degrader) .
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