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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
PROTAC SMARCA2 degrader-8
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "PROTAC SMARCA2 degrader-8" in MCE Product Catalog:
Cat. No.: HY-161882
CAS No.: 2669027-50-1
Target:
Research Areas:
PROTAC SMARCA2 degrader-8 is a SMARCA2 PROTAC degrader with a DC50 of 28 nM in A375 cells. PROTAC SMARCA2 degrader-8 forms a crystallizable ternary complex with the SMARCA4 bromodomain and VBC, promoting the ubiquitination and proteasomal degradation of SMARCA2. PROTAC SMARCA2 degrader-8 can be used in melanoma research .
Cat. No.: HY-159460
CAS No.: 2568507-14-0
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Research Areas:
PROTAC SMARCA2/4 degrader-8 is a SMARCA2/SMARCA4 PROTAC degrader. PROTAC SMARCA2/4 degrader-8 induces ubiquitination, proteasome-mediated degradation, and recruits the E3 ubiquitin ligase complex. PROTAC SMARCA2/4 degrader-8 is applicable for cancer-related research .
Cat. No.: HY-W063924
CAS No.: 1166829-70-4
Synonyms: Ethyl-2-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3- enyl)acetate
Target:
Research Areas:
Bpin-Cyclohexene-C-COOEt is a PROTAC linker. Bpin-Cyclohexene-C-COOEt can be used in synthesis PROTAC SMARCA2/4-degrader-8 (HY-159460) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
