1 Result for "

PROTECs

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PROTECs" in MCE Product Catalog:

Cat. No.: HY-189001
Target:  

NAMPT PROTECs

Research Areas:  

Cancer

PROTEC NAMPT Degrader-1 is a NAMPT PROTEC degrader. PROTEC NAMPT Degrader-1 binds to NAMPT via non-covalent interactions and degrades this protein through a proximity-induced radical oxidation mechanism mediated by cyclopropane radical clock, independent of proteasomal or lysosomal pathways. PROTEC NAMPT Degrader-1 exhibits anticancer activity against ovarian cancer. It can be used in relevant studies on ovarian cancer (Pink: NAMPT ligand: (HY-188123); Linker: (HY-188124)) .
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