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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Pigmentation Inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Pigmentation Inhibitor" in MCE Product Catalog:
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Cat. No.: HY-W251181
CAS No.: 1428450-95-6
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Isobutylamido thiazolyl resorcinol is a selective hTyr inhibitor with an IC50 of 1.1 μM. Isobutylamido thiazolyl resorcinol shows an IC50 of 108 μM against mushroom Tyrosinase. Isobutylamido thiazolyl resorcinol effectively prevents pigmentation caused by UVB irradiation. Isobutylamido thiazolyl resorcinol significantly improves the visibility of acne-induced hyperpigmentation .
Cat. No.: HY-P10533
CAS No.: 845727-64-2
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Cat. No.: HY-N12267
CAS No.: 42369-86-8
Synonyms: (E/Z)-Terrestribisamide
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Cat. No.: HY-148400
CAS No.: 913541-96-5
Synonyms: TXC hydrochloride
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Cetyl tranexamate (TXC) hydrochloride is an ester derivative of Tranexamic acid (HY-B0149). Cetyl tranexamate hydrochloride is an inhibitor of fibrinogen activation and can reduce the production of fibrinogen in keratinocytes induced by ultraviolet rays or damage, indirectly inhibiting the melanin production pathway. Cetyl tranexamate hydrochloride also targets melanin (dark spots) and hemoglobin (red spots), reducing vascular dilation and pigmentation by inhibiting inflammatory mediators (such as prostaglandins, platelet activating factors). Cetyl tranexamate hydrochloride can be used as a cosmetic ingredient and is suitable for epidermal pigment disorders such as photoaging, post-inflammatory hyperpigmentation (PIH), and melasma .
Cat. No.: HY-121889
CAS No.: 190838-76-7
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FQ is a tyrosinase inhibitor that effectively inhibits the diphenolase activity of mushroom tyrosinase (IC50=120 μM). FQ can be used in the study of pigmentation .
Cat. No.: HY-161969
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Tyrosinase-IN-34 (compound 5a) is a human tyrosinase inhibitor (IC50: 3.5 μM) with the potential to control melanogenesis and pigmentation .
Cat. No.: HY-173512
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mTYR-IN-1 (compound 3e) is a reversible and competitive mTYR inhibitor with an IC50 of 4.86 μM. mTYR-IN-1 can be used in the study of skin pigmentation .
Synonyms: trans-10-Pentadecenoic acid
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10 (E)-Pentadecenoic acid (trans-10-Pentadecenoic acid) is a melanin synthesis inhibitor. 10 (E)-Pentadecenoic acid inhibits nuclear translocation and reduces the protein level of phosphorylated microphthalmia-associated transcription factor (MITF), as well as decreases intracellular tyrosinase activity. 10 (E)-Pentadecenoic acid can be used in the research of skin pigmentation disorders .
Cat. No.: HY-N0113A
CAS No.: 62493-39-4
Synonyms: Ordenina sulfate; Peyocactine sulfate
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Cat. No.: HY-N3773
CAS No.: 1372527-25-7
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Cat. No.: HY-179619
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Tyrosinase-IN-46 (Compound III19) is a tyrosinase inhibitor. Its IC50 values for L-dopa and L-tyrosine are 3.24 and 2.79 nM respectively. Tyrosinase-IN-46 inhibits melanin synthesis and shows a significant anti-pigmentation effect. Tyrosinase-IN-46 can be used for the study of pigmentation disorders .
Cat. No.: HY-179100
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Tyrosinase-IN-45 (compound 4) is a tyrosinase inhibitor (IC50 = 1.51 μM). Tyrosinase-IN-45 can reduce the melanin content. Tyrosinase-IN-45 can be used for skin whitening and improving pigmentation .
Cat. No.: HY-N10337
CAS No.: 74119-87-2
Synonyms: (-)-Norjuziphine
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Cat. No.: HY-184907
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AI10-m15 is a tyrosinase inhibitor, with IC50 values of 0.019 μM (using L-DOPA (HY-N0304) as the substrate) and 0.02 μM (using L-Tyrosine (HY-N0473) as the substrate) against mushroom tyrosinase. AI10-m15 inhibits intracellular melanin production and reduces head pigmentation in zebrafish embryos. AI10-m15 can be used for the research of hyperpigmentation disorders .
Cat. No.: HY-184909
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AI10-a2 is a tyrosinase (tyrosinase) inhibitor, with IC50 values of 0.92 μM against mushroom tyrosinase using L-DOPA (HY-N0304) as the substrate and 0.68 μM using L-Tyrosine (HY-N0473) as the substrate. AI10-a2 inhibits intracellular melanin (melanin) production and reduces head pigmentation in zebrafish embryos. AI10-a2 can be used for the research of hyperpigmentation disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
