4-Bromobenzoic acid
Based on 1 Customer Validation
4-Bromobenzoic acid is a tyrosinase inhibitor (IC50 range 0-0.3 mg/mL). 4-Bromobenzoic acid can be metabolized through the protocatechuic acid (PCA) pathway. 4-Bromobenzoic acid can be used for research on cosmetic whitening or pigmentation conditions.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 586-76-5
- Formula: C7H5BrO2
- Molecular Weight:201.02
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 586-76-5
-
Appearance Solid
-
Molecular Weight 201.02
-
Formula C7H5BrO2
-
Color White to off-white
-
SMILES
BrC1=CC=C(C(O)=O)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (497.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
-
Handling Instructions (2659 KB)
References
[1]. 4-Bromobenzoic acid [Content Brief]
[2]. Nicolson GL, Singer SJ. Ferritin-conjugated plant agglutinins as specific saccharide stains for electron microscopy: application to saccharides bound to cell membranes. Proc Natl Acad Sci U S A. 1971 May;68(5):942-5. [Content Brief]
[3]. Adebusoye SA. Biological degradation of 4-chlorobenzoic acid by a PCB-metabolizing bacterium through a pathway not involving (chloro)catechol. Biodegradation. 2017 Feb;28(1):37-51. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9747 mL | 24.8733 mL | 49.7465 mL | 124.3664 mL |
| 5 mM | 0.9949 mL | 4.9747 mL | 9.9493 mL | 24.8733 mL | |
| 10 mM | 0.4975 mL | 2.4873 mL | 4.9747 mL | 12.4366 mL | |
| 15 mM | 0.3316 mL | 1.6582 mL | 3.3164 mL | 8.2911 mL | |
| 20 mM | 0.2487 mL | 1.2437 mL | 2.4873 mL | 6.2183 mL | |
| 25 mM | 0.1990 mL | 0.9949 mL | 1.9899 mL | 4.9747 mL | |
| 30 mM | 0.1658 mL | 0.8291 mL | 1.6582 mL | 4.1455 mL | |
| 40 mM | 0.1244 mL | 0.6218 mL | 1.2437 mL | 3.1092 mL | |
| 50 mM | 0.0995 mL | 0.4975 mL | 0.9949 mL | 2.4873 mL | |
| 60 mM | 0.0829 mL | 0.4146 mL | 0.8291 mL | 2.0728 mL | |
| 80 mM | 0.0622 mL | 0.3109 mL | 0.6218 mL | 1.5546 mL | |
| 100 mM | 0.0497 mL | 0.2487 mL | 0.4975 mL | 1.2437 mL |
4-Bromobenzoic acid Related Classifications
HY-78700 Related Classifications
Powered by Bioz