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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
Protein Phosphatase 5
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "Protein Phosphatase 5" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
Ro 90-7501 is an amyloid β42 (Aβ42) fibril assembly inhibitor that reduces Aβ42-induced cytotoxicity (EC50 of 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response . Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner . Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells .
Target:
Research Areas:
DJ001 is a highly specific, selective and non-competitive protein tyrosine phosphatase-σ (PTPσ) inhibitor with an IC50 of 1.43 μM. DJ001 displays no inhibitory activity against other phosphatases, with only modest inhibitory activity against Protein Phosphatase 5. DJ001 promotes promote hematopoietic stem cell regeneration .
Target:
Research Areas:
PP5-IN-1 is a competitive and selective serine/threonine protein phosphatase 5 (PP5) inhibitor with a Ki value of 244 nM. PP5-IN-1 induces extrinsic apoptosis (Apoptosis), disrupts the integrity of complex II, and activates Caspase 8. PP5-IN-1 can be used in research related to clear cell renal cell carcinoma .
Cat. No.: HY-P81324
Synonyms: FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; PPP5; PPP5_HUMAN; PPP5C; PPT; Protein Phosphatase 5; catalytic subunit; Protein Phosphatase T; Serine/threonine Protein Phosphatase 5; Serine/threonine-Protein Phosphatase 5.
Cat. No.: HY-169013
CAS No.: 2923531-63-7
Target:
Research Areas:
DDO-3733 is a TRP-independent Protein Phosphatase 5 (PP5) allosteric activator that promotes dephosphorylation of downstream substrates .
Cat. No.: HY-P85519
Synonyms: FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; PPP5; PPP5_HUMAN; PPP5C; PPT; Protein Phosphatase 5, catalytic subunit; Protein Phosphatase T; Serine/threonine Protein Phosphatase 5; Serine/threonine-Protein Phosphatase 5.
Cat. No.: HY-169002
Target:
Research Areas:
PP5-IN-2 is an orally active and selective protein phosphatase 5 (PP5) inhibitor with an IC50 value of 0.9 μM. PP5-IN-2 activates p53 and downregulates cyclin D1 and MGMT, which shows potency in cell cycle arrest and reverses Temozolomide (TMZ) (HY-17364) resistance in the U87 MG cell line. PP5-IN-2 effectively inhibits tumor growth in the xenograft mouse model .
Cat. No.: HY-P75540
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACP5; TrATPase; Acid Phosphatase 5, Tartrate Resistant; Tartrate-Resistant Acid Phosphatase 5a; Tartrate-Resistant Acid Phosphatase Type 5; Tartrate-Resistant Acid Phosphatase 5b; TRAcP; Tartrate-Resistant Acid Phosphatase; TRAP; Type 5 Acid Phosphatase;
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P75561
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACP5; TrATPase; Acid Phosphatase 5, Tartrate Resistant; Tartrate-Resistant Acid Phosphatase 5a; Tartrate-Resistant Acid Phosphatase Type 5; Tartrate-Resistant Acid Phosphatase 5b; TRAcP; Tartrate-Resistant Acid Phosphatase; TRAP; Type 5 Acid Phosphatase;
Species:
Human
Source:
HEK293
Cat. No.: HY-P70834
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INPP5A; InsP3 5-Phosphatase; Inositol Polyphosphate-5-Phosphatase A; Type I Inositol-1,4,5-Trisphosphate 5-Phosphatase; 5PTASE; Type I Inositol-1,4,5-Trisphosphate 5-Phophatase; Type I Inositol 1,4,5-Trisphosphate 5-Phosphatase; Inositol Polyphosphate 5-P
Species:
Human
Source:
HEK293
Cat. No.: HY-103241R
CAS No.: 293762-45-5
Research Areas:
Ro 90-7501 (Standard) is the analytical standard of Ro 90-7501 (HY-103241). This product is intended for research and analytical applications. Ro 90-7501 is an amyloid β42 (Aβ42) fibril assembly inhibitor that reduces Aβ42-induced cytotoxicity (EC50 of 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response . Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner . Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells .
Cat. No.: HY-P7448
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NT5E; ENT; Prev. NT5; 5'-NT; IMP-Specific 5'-Nucleotidase; NTE; Thymidylate 5'-Phosphatase; 5'-Nucleotidase, Ecto (CD73); 5'-Deoxynucleotidase; Purine 5-Prime-Nucleotidase; Ecto-5'-Nucleotidase; 5' Nucleotidase (CD73); 5'-Nucleotidase; CD73 Antigen; CALJA
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P7836
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NT5E; ENT; Prev. NT5; 5'-NT; IMP-Specific 5'-Nucleotidase; NTE; Thymidylate 5'-Phosphatase; 5'-Nucleotidase, Ecto (CD73); 5'-Deoxynucleotidase; Purine 5-Prime-Nucleotidase; Ecto-5'-Nucleotidase; 5' Nucleotidase (CD73); 5'-Nucleotidase; CD73 Antigen; CALJA
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P7449
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NT5E; ENT; Prev. NT5; 5'-NT; IMP-Specific 5'-Nucleotidase; NTE; Thymidylate 5'-Phosphatase; 5'-Nucleotidase, Ecto (CD73); 5'-Deoxynucleotidase; Purine 5-Prime-Nucleotidase; Ecto-5'-Nucleotidase; 5' Nucleotidase (CD73); 5'-Nucleotidase; CD73 Antigen; CALJA
Species:
Rat
Source:
HEK293
Cat. No.: HY-P78610
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NT5E; ENT; Prev. NT5; 5'-NT; IMP-Specific 5'-Nucleotidase; NTE; Thymidylate 5'-Phosphatase; 5'-Nucleotidase, Ecto (CD73); 5'-Deoxynucleotidase; Purine 5-Prime-Nucleotidase; Ecto-5'-Nucleotidase; 5' Nucleotidase (CD73); 5'-Nucleotidase; CD73 Antigen; CALJA
Species:
Rabbit
Source:
HEK293
Cat. No.: HY-P78638
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NT5E; ENT; Prev. NT5; 5'-NT; IMP-Specific 5'-Nucleotidase; NTE; Thymidylate 5'-Phosphatase; 5'-Nucleotidase, Ecto (CD73); 5'-Deoxynucleotidase; Purine 5-Prime-Nucleotidase; Ecto-5'-Nucleotidase; 5' Nucleotidase (CD73); 5'-Nucleotidase; CD73 Antigen; CALJA
Species:
Canine
Source:
HEK293
Cat. No.: HY-P704489
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NT5E; ENT; Prev. NT5; 5'-NT; IMP-Specific 5'-Nucleotidase; NTE; Thymidylate 5'-Phosphatase; 5'-Nucleotidase, Ecto (CD73); 5'-Deoxynucleotidase; Purine 5-Prime-Nucleotidase; Ecto-5'-Nucleotidase; 5' Nucleotidase (CD73); 5'-Nucleotidase; CD73 Antigen; CALJA
Species:
Human
Source:
HEK293
Cat. No.: HY-P74272
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NT5E; ENT; Prev. NT5; 5'-NT; IMP-Specific 5'-Nucleotidase; NTE; Thymidylate 5'-Phosphatase; 5'-Nucleotidase, Ecto (CD73); 5'-Deoxynucleotidase; Purine 5-Prime-Nucleotidase; Ecto-5'-Nucleotidase; 5' Nucleotidase (CD73); 5'-Nucleotidase; CD73 Antigen; CALJA
Species:
Human
Source:
HEK293
Cat. No.: HY-P77534
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: NT5E; ENT; Prev. NT5; 5'-NT; IMP-Specific 5'-Nucleotidase; NTE; Thymidylate 5'-Phosphatase; 5'-Nucleotidase, Ecto (CD73); 5'-Deoxynucleotidase; Purine 5-Prime-Nucleotidase; Ecto-5'-Nucleotidase; 5' Nucleotidase (CD73); 5'-Nucleotidase; CD73 Antigen; CALJA
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
