Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
PtdIns(3,4,5)-P3
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "PtdIns(3,4,5)-P3" in MCE Product Catalog:
Cat. No.: HY-132276
CAS No.: 1415684-80-8
Target:
Research Areas:
PtdIns-(3,4,5)-P3-biotin sodium is a Biotin-labeled PtdIns-(3,4,5)-P3 (PI(3,4,5)P3). PI(3,4,5)P3 is a substrate of nuclear phosphatidylinositol 5-phosphatase (PIP5Pase). PI(3,4,5)P3 binds to the N-terminus of RAP1 (repressor activator protein 1) and controls its DNA binding activity .
Synonyms: Phosphatidylinositol tris-3,4,5-phosphate, 1,2-dipalmitoyl sodium
Target:
Research Areas:
PtdIns-(345)-P3 (12-dipalmitoyl) sodium (Phosphatidylinositol tris-3,4,5-phosphate, 1,2-dipalmitoyl sodium) is a phosphatidylinositol 3,4,5-trisphosphate (PIP3) analog. PtdIns-(345)-P3 (12-dipalmitoyl) sodium can be incorporated in liposomes establish a backdrop of membrane phospholipids that closely mirrors in vivo conditions .
Cat. No.: HY-175086
Synonyms: DOPI-3,4,5-P3-fluorescein triethylammonium; PI(3,4,5)P3-fluorescein triethylammonium; PIP3[3',4',5']-fluorescein triethylammonium
Target:
Research Areas:
PtdIns-(3,4,5)-P3 is a second messenger. PtdIns-(3,4,5)-P3-fluorescein triethylammonium is a fluorescent probe that can detect any protein that has a high-affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids .
Cat. No.: HY-175407
Target:
Research Areas:
18:0-20:4 PI(3,4,5)P3 (sodium) is an analogue of phosphatidylinositol. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific PLC .
Cat. No.: HY-141420
CAS No.: 799268-62-5
Target:
Research Areas:
PtdIns-(3,4,5)-P3(1,2-dihexanoyl) ammonium (compound 850176) is a vaccine adjuvant that enhances the immune function of vaccines .
Cat. No.: HY-175089
Synonyms: DOPI-3,4,5-P3 sodium; PIP3[3',4',5'](8:0/8:0) sodium; PI(3,4,5)P3 (8:0/8:0) sodium
Target:
Research Areas:
PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (DOPI-3,4,5-P3) sodium is an analog of phosphatidylinositol .
Cat. No.: HY-179543
Target:
Research Areas:
PtdIns-(3,4,5)-P3-(1-stearoyl, 2-arachidonoyl) sodium is a specific molecular form of phosphatidylinositol-3,4,5-trisphosphate (PIP3). PIP3 is the core lipid messenger in the tyrosine kinase pathway, regulating cell proliferation, survival and metabolism by recruiting effector proteins. Its abnormality is associated with cancer. PtdIns-(3,4,5)-P3-(1-stearoyl, 2-arachidonoyl) sodium can be used for studying lipid signal transduction .
Cat. No.: HY-175083
Target:
Research Areas:
PtdIns-(4,5)-P2-biotin trisodium is a Biotin-labeled PtdIns-(4,5)-P2 analog. PtdIns-(4,5)-P2-biotin trisodium is an affinity probe of PI3Kγ. PI3Kγ can catalyse the phosphorylation of PtdIns-(4,5)-P2 at the 3′-OH group, giving rise to the second messenger PtdIns(3,4,5)-P3 .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
