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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
RBL cells
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "RBL cells" in MCE Product Catalog:
2
Category:
Plants other families Flavonoids Functional Molecules Research of Health Products Phenols Polyphenols Disease Research Fields Inflammation/Immunology Biflavones
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2
2 Cited Publications
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Syk Inhibitor II is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II shows less potent against other kinases and has anti-allergic effect .
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1 Cited Publications
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15(S)-HETRE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.
Cat. No.: HY-113337A
CAS No.: 102783-36-8
Synonyms: P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium
Ap4A tetraammonium (P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium) is a conserved second messenger in organisms ranging from bacteria to humans. Ap4A tetraammonium binds to the histidine triad nucleotide-binding protein 1 (HINT1) activates the transcription of genes downstream of MITF. Ap4A tetraammonium induces apoptosis .
Cat. No.: HY-N2252
CAS No.: 51020-86-1
Synonyms: (+)-Licarin A
Category:
Neurological Disease Saururus chinensis (Lour.) Baill. Plants Saururaceae Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-P1640
CAS No.: 130154-64-2
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Cat. No.: HY-N15708
CAS No.: 755036-45-4
Synonyms: (R)-(-)-Dichotomine C
Cat. No.: HY-112390
CAS No.: 227449-73-2
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Syk Inhibitor II dihydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride shows less potent against other kinases and has anti-allergic effect .
Cat. No.: HY-W013727
CAS No.: 136647-02-4
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UK-78282 hydrochloride is a KV1.3 channel inhibitor with an IC50 value of 0.20 μM and a Kd of 0.39 μM. UK-78282 hydrochloride also inhibits the Kv1.4 Potassium Channel. UK-78282 hydrochloride blocks KV1.3 in a use-dependent manner and inhibits human T lymphocyte activation by regulating the cell cycle. UK-78282 hydrochloride can be used in research related to mental disorders, such as depression and schizophrenia .
Cat. No.: HY-N12116
CAS No.: 1967042-42-7
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Cat. No.: HY-P11128
CAS No.: 1427516-68-4
Cat. No.: HY-139247
CAS No.: 2454246-25-2
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pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM .
Cat. No.: HY-P11163
CAS No.: 255720-68-4
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Cat. No.: HY-N12231
CAS No.: 75139-38-7
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Cat. No.: HY-N2344R
CAS No.: 103883-03-0
Synonyms: Proanthocyanidin A1 (Standard)
Category:
other families Flavonoids Phenols Polyphenols Plants Biflavones
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MRS2690 is a selective P2Y14 receptor agonist. MRS2690 inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690can be used for ischemic heart disease .
Cat. No.: HY-112390C
CAS No.: 2490508-82-0
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Syk Inhibitor II hydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II hydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II hydrochloride shows less potent against other kinases and has anti-allergic effect .
Cat. No.: HY-116295A
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MRS2690 disodium is a selective P2Y14 receptor agonist. MRS2690 disodium inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 disodium induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690 disodium can be used for ischemic heart disease .
Cat. No.: HY-112390B
CAS No.: 1965323-05-0
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Syk Inhibitor II dihydrochloride dihydrate is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride dihydrate inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride dihydrate shows less potent against other kinases and has anti-allergic effect .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
