2490508-82-0
2490508-82-0
Chemical Structure
Syk Inhibitor II hydrochloride
- CAS 番号: 2490508-82-0
- Formula:C14H16ClF3N6O
- Molecular Weight:376.76
IUPAC Name: 2-((2-aminoethyl)amino)-4-((3-(trifluoromethyl)phenyl)amino)pyrimidine-5-carboxamide hydrochloride
InChIKey: PVURZQHSTKFHCH-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.Cl
Biological Activity: Syk Inhibitor II hydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II hydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II hydrochloride shows less potent against other kinases and has anti-allergic effect[1].
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Syk Inhibitor II hydrochloride | Syk Inhibitor II hydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II hydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II hydrochloride shows less potent against other kinases and has anti-allergic effect. | |||||||||||||||||||||
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