1 Result for "

RD-HGA16 cells

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "RD-HGA16 cells" in MCE Product Catalog:

Cat. No.: HY-129215
CAS No.: 652978-45-5
RTI-371 is a highly selective atypical dopamine transporter (DAT) inhibitor that crosses the blood-brain barrier. RTI-371 exhibits potent inhibitory activity in cell lines transfected with human DAT (IC50 = 8.7 nM) and shows high binding affinity for rat DAT with a Ki value of 7.81 nM. RTI-371 also acts as a positive allosteric modulator of the human cannabinoid 1 receptor (hCB1 receptor), enhancing the activity of cannabinoid receptor agonists in a concentration-dependent manner. RTI-371 can be used for the research of Parkinson's disease .
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