2 Results for "

Ro 18-5364

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Ro 18-5364" in MCE Product Catalog:

Cat. No.: HY-115312
CAS No.: 101387-98-8
Target:  

Na+/K+ ATPase

Research Areas:  

Others

Ro 18-5364 is an inhibitor of gastric H+/K+ ATPase, which has the effect of inhibiting the activity of the enzyme. Ro 18-5364 has a very strong inhibitory effect on gastric mucosal H+/K+ ATPase, and the inhibitory effect is more significant at low pH. At the same time, there is no selectivity difference between the two enantiomers of H+/K+ ATPase, and its inhibitory effect can be studied and verified by a variety of experimental methods, including inhibition of enzyme activity, proton transport, and studies on its binding.
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Cat. No.: HY-U00193
CAS No.: 101387-97-7
Target:  

Na+/K+ ATPase

Research Areas:  

Metabolic Disease

Ro18-5362 is the less active proagent of Ro 18-5364. Even at concentrations as high as 0.1 mM Ro 18-5362 fails to affect significantly (H ++K +)-ATPase activity and associated proton translocation.
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