3 Results for "

Ruxolitinib phosphate (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Ruxolitinib phosphate (Standard)" in MCE Product Catalog:

Cat. No.: HY-50858R
CAS No.: 1092939-17-7
Synonyms: INCB018424 phosphate (Standard)
Ruxolitinib phosphate (Standard) is the analytical standard of Ruxolitinib phosphate (HY-50858). This product is intended for research and analytical applications. Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC50s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3.
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Cat. No.: HY-50856R
CAS No.: 941678-49-5
Synonyms: INCB18424 (Standard)
Research Areas:  

Cancer

Ruxolitinib (Standard) is the analytical standard of Ruxolitinib. This product is intended for research and analytical applications. Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3 . Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy .
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Cat. No.: HY-W059210
CAS No.: 952518-97-7
Research Areas:  

Others

Ruxolitinib impurity-1 is a pyrrolopyrimidine derivative and also an impurity of Ruxolitinib (HY-50856). Ruxolitinib serves as a synthetic intermediate for TDM-180967, a dual JAK1/Tyk2 inhibitor, and can also be used as an impurity reference standard for drug quality control .
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