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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
70 Results for "
S-7
" in MedChemExpress (MCE) Product Catalog:
Products (70)
70 Results for "S-7" in MCE Product Catalog:
1
1 Cited Publications
Referencia número: HY-P10284
No. CAS: 853248-13-2
Target:
Áreas de investigación:
34
34 Publications Verification
Synonyms: Necrostatin 1S; Nec-1S; 7-Cl-O-Nec1
Target:
Áreas de investigación:
Necrostatin 2 racemate (Nec-1S), the Necrostatin-1 (HY-15760) stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect .
2
1
1 Cited Publications
Target:
Áreas de investigación:
SecinH3 is an antagonist of cytohesins with IC50s of 5.4 μM, 2.4 μM, 5.4 μM, 5.6 μM, 5.6 μM and 65 μM for hCyh1, hCyh2, mCyh3, hCyh3, drosophila steppke and yGea2-S7, respectively.
Referencia número: HY-159520
No. CAS: 2731294-23-6
Synonyms: Ofirnoflast; HT-6184
Áreas de investigación:
Ofirnoflastum (Ofirnoflast) is an orally active first-in-class allosteric NEK7 inhibitor with an IC50 of 46 nM. Ofirnoflastum binds an allosteric site adjacent to NEK7’s ATP-binding pocket, induces conformational shifts, disrupts NEK7-NLRP3 binding, blocks NLRP3 inflammasome assembly, spares NEK7’s physiological functions, and suppresses caspase-1, caspase-8, NF-κB, and TNF activity. Ofirnoflastum reduces pro-inflammatory cytokine production, suppresses ASC specks, IL-1β release, pyroptotic cell death, and leukemic burden, induces apoptosis and erythroid differentiation, restores hematopoiesis, and improves outcomes in colitis models. Ofirnoflastum can be used for the research of myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia .
Referencia número: HY-W106164A
No. CAS: 2820537-15-1
Target:
Áreas de investigación:
((2S,7aS)-2-Fluorohexahydro-1H-pyrrolizin-7a-yl)methanol is a drug intermediate for synthesis of various active compounds.
Referencia número: HY-133885
No. CAS: 856925-75-2
Referencia número: HY-N2207
No. CAS: 178740-32-4
Category:
Other Diseases Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.
Target:
Referencia número: HY-W091788
No. CAS: 908130-61-0
Target:
Áreas de investigación:
(2S,3R,5S)-7-Deaza-2'-deoxy-7-iodoadenosine is the isomer of 7-Deaza-2'-deoxy-7-iodoadenosine (HY-W048490), and can be used as an experimental control. 7-Deaza-2'-deoxy-7-iodoadenosine is a modified oligonucleotide containing 7-Deazaadenine .
Referencia número: HY-174129
No. CAS: 2649008-95-5
TM471-1 is an orally active and covalent Bruton's tyrosine kinase (BTK) inhibitor with IC50 values of 1.3 nM (BTK WT), >40,000 nM (BTK C481S), 7.9 nM (TEC) and 12.4 nM (TXK). TM471-1 inhibits cell growth in vivo and in vitro, arrests cell cycle at G0/G1 phase and induces cell apoptosis .
Referencia número: HY-N0291R
No. CAS: 29745-04-8
Target:
Áreas de investigación:
(±)-Norcantharidin (Standard) is the analytical standard of (±)-Norcantharidin. This product is intended for research and analytical applications. (±)-Norcantharidin ((±)-NCTD) is a compound possessing anti-angiogenetic activity with potential use in anti-cancertherapy. (±)-Norcantharidin could prevent tumorigenesis by inhibiting cell proliferation, inducing apoptosis and the cell cycle arrest, and anti-angiogenic effects .
Referencia número: HY-163892
Target:
Áreas de investigación:
POLRMT-IN-1 (compound S7) is a POLRMT inhibitor. POLRMT-IN-1 can be used in cancer-related research .
Referencia número: HY-W742809
No. CAS: 63740-81-8
Target:
Áreas de investigación:
(S)-7-Hydroxywarfarin is the S stereoisomer of 7-Hydroxywarfarin (HY-139167). (S)-7-Hydroxywarfarin is the inactive, major metabolite of racemic Warfarin (HY-B0687) .
Referencia número: HY-162578
Target:
Áreas de investigación:
PPARα/γ agonist 4 (Compound (S)-7) is an orally active dual potent agonist of PPARα and PPARγ, with EC50 values of 0.061 μM and 1.42 μM respectively. PPARα/γ agonist 4 acts through an insulin-independent mechanism and exhibits mitochondrial pyruvate carrier inhibition and anti-diabetic properties. PPARα/γ agonist 4 is expected to be used in research for dyslipidemic type 2 diabetes .
Referencia número: HY-N2747
No. CAS: 100079-34-3
Target:
Referencia número: HY-B0395DS
Synonyms: (1R,2S,7R)-DU6859a-d4 hydrochloride
Referencia número: HY-N12068
No. CAS: 214627-06-2
Target:
Referencia número: HY-N2738
No. CAS: 376361-96-5
Target:
Referencia número: HY-W095672AS4
No. CAS: 2883770-63-4
Synonyms: (2S,7aR)-2-Fluorotetrahydro-1H-pyrrolizine-7a(5H)-methanol-d2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
