4 Results for "

S9 metabolic activation

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "S9 metabolic activation" in MCE Product Catalog:

Cat. No.: HY-N18080
CAS No.: 508-59-8
Parthenin is a pseudoguaianolide-type sesquiterpene lactone present in Parthenium hysterophorus L. Parthenin induces chromosomal aberrations, mainly chromatid breaks, in human peripheral blood lymphocytes. Parthenin exhibits toxicity against Salmonella typhimurium and Escherichia coli strains, with reduced toxicity in the presence of a metabolic activation system (S9). Parthenin acts as an antifeedant against the 6th instar larvae of the tobacco cutworm (Spodoptera litura). Parthenin shows insecticidal activity against adult cowpea weevils (Callosobruchus maculatus). Parthenin inhibits seed germination and seedling growth of sicklepod (Cassia tora). Parthenin possesses nematicidal activity against the 2nd instar larvae of the southern root-knot nematode (Meloidogyne incognita). Parthenin serves as a research agent for studies related to cancer, malaria, amoebiasis, inflammatory diseases, and bacterial infections .
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Cat. No.: HY-129862
CAS No.: 67450-45-7
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

Eclanamine maleate is an orally effective non-tricyclic antidepressant and an adrenergic receptor modulator. Eclanamine maleate blocks biogenic amine uptake and enhances α2-receptor sensitivity, and long-term administration induces downregulation and desensitization of cortical β-receptors. Eclanamine maleate is used in the study of depression .
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Cat. No.: HY-129862A
CAS No.: 67450-44-6
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

Eclanamine is an orally effective non-tricyclic antidepressant and an adrenergic receptor modulator. Eclanamine blocks biogenic amine uptake and enhances α2-receptor sensitivity, and long-term administration induces downregulation and desensitization of cortical β-receptors. Eclanamine is used in the study of depression .
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Cat. No.: HY-153507
CAS No.: 1137671-16-9
Target:  

Acyltransferase

Research Areas:  

Metabolic Disease

DGAT1-IN-4 is a potent, orally active, and selective DGAT1 inhibitor with an IC50 of 17 nM. DGAT1-IN-4 exhibits >588-fold selectivity over DGAT2. DGAT1-IN-4 suppresses intracellular triglyceride synthesis in mouse myoblast cells. DGAT1-IN-4 suppresses body weight gain in diet-induced obese dogs. DGAT1-IN-4 can be used for the research of obesity .
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