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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

SIRPa/CD172a Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD47 (3)
By Research Areas:	Cancer (1) Inflammation/Immunology (2)

Inhibitors & Agonists

Inhibitory Antibodies

Targets Recommended:

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P991693

Ipsoprubart ELA-026	CD47	Inflammation/Immunology
Ipsoprubart is a humanized IgG1κ antibody targeting *SIRPa/CD172a*. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P990555

BI-765063 OSE-172	CD47	Inflammation/Immunology
BI-765063 (OSE-172) is a humanized antibody expressed in CHO that targets *SIRPa/CD172a*. BI-765063 contains an IgG4-type heavy chain and a huκ-type light chain, with a predicted molecular weight (MW) of 146.3 kDa. The isotype control for BI-765063 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P992346

DS-1103a	CD47	Cancer
DS-1103a is a humanized IgG4 monoclonal antibody targeting *SIRPa/CD172a. DS-1103a inhibits the interaction between SIRPα and CD47. DS-1103a enhances antibody*-dependent cellular phagocytosis of cancer cells. DS-1103a can be used for the research of solid tumors. The recommended isotype control is: Human IgG4 (S228P) kappa, (HY-P99003) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991693

Ipsoprubart ELA-026	CD47	Inflammation/Immunology
Ipsoprubart is a humanized IgG1κ antibody targeting *SIRPa/CD172a*. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P990555

BI-765063 OSE-172	CD47	Inflammation/Immunology
BI-765063 (OSE-172) is a humanized antibody expressed in CHO that targets *SIRPa/CD172a*. BI-765063 contains an IgG4-type heavy chain and a huκ-type light chain, with a predicted molecular weight (MW) of 146.3 kDa. The isotype control for BI-765063 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P992346

DS-1103a	CD47	Cancer
DS-1103a is a humanized IgG4 monoclonal antibody targeting *SIRPa/CD172a. DS-1103a inhibits the interaction between SIRPα and CD47. DS-1103a enhances antibody*-dependent cellular phagocytosis of cancer cells. DS-1103a can be used for the research of solid tumors. The recommended isotype control is: Human IgG4 (S228P) kappa, (HY-P99003) .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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