Search Result

Results for "

SN

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (9) ACSL Family (1) Acyltransferase (1) ADC Linker (5) ADC Payload (3) Aldose Reductase (1) Amino Acid Derivatives (1) Amino acid Transporter (1) Amyloid-β (2) Antibiotic (1) Antibody-Drug Conjugates (ADCs) (6) Apoptosis (22) ASCT (3) Autophagy (8) Bacterial (9) Bcl-2 Family (3) BCRP (3) Biochemical Assay Reagents (186) Calcium Channel (1) Carnitine Palmitoyltransferase (CPT) (1) Caspase (4) CCR (1) CD1 (1) CDK (1) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (3) CRFR (1) Cytochrome P450 (2) Dengue Virus (2) DGK (1) DNA Alkylator/Crosslinker (4) DNA/RNA Synthesis (1) Drug Derivative (19) Drug Intermediate (8) Drug Isomer (3) Drug Metabolite (6) Drug-Linker Conjugates for ADC (13) EAAT (4) EGFR (1) Endogenous Metabolite (125) Environmental Pollutants (2) ERK (1) FABP (1) Fatty Acid Synthase (FASN) (2) Ferroptosis (4) Flavivirus (2) Fluorescent Dye (7) Fungal (1) GLP Receptor (1) GLUT (1) Glutathione Peroxidase (1) Glycosidase (2) HBV (1) HCV (1) HDAC (2) Herbicide (1) HIF/HIF Prolyl-Hydroxylase (2) Histone Methyltransferase (1) HIV (4) iGluR (1) Interleukin Related (3) Isotope-Labeled Compounds (135) Lipase (3) Lipocalin Family (1) Liposome (157) LPL Receptor (7) MDM-2/p53 (2) Microtubule/Tubulin (1) Mitochondrial Metabolism (2) Mitophagy (5) Mitosis (2) MOFs (3) mTOR (3) Na+/Ca2+ Exchanger (2) Na+/K+ ATPase (1) NADPH Oxidase (1) Neurotensin Receptor (1) NF-κB (3) NOD-like Receptor (NLR) (1) p38 MAPK (2) Parasite (7) PARP (3) Peptide-Drug Conjugates (PDCs) (1) Phosphatase (1) Phosphoglycerate Dehydrogenase (PHGDH) (1) Phospholipase (12) PI3K (2) PKC (9) Platelet-activating Factor Receptor (PAFR) (2) PPAR (4) PROTACs (2) Ras (1) Reactive Oxygen Species (ROS) (6) Reference Standards (19) RET (1) ROCK (1) Scavenger Receptor Class B type I (SR-BI） (2) Small Interfering RNA (siRNA) (4) Sodium Channel (1) STAT (2) STING (4) TGF-beta/Smad (1) TGF-β Receptor (1) Thrombin (1) TNF Receptor (2) Topoisomerase (16) TROP2 (2) TRP Channel (4) UGT (1) VD/VDR (1) VEGFR (1) β-glucuronidase (1)
By Research Areas:	Cancer (139) Cardiovascular Disease (26) Endocrinology (2) Infection (21) Inflammation/Immunology (32) Metabolic Disease (199) Neurological Disease (36)
Click Chemistry:	Azide (5) Alkynes (1)
Oligonucleotides:	Fluorescent Lipids (1) Pegylated Lipids (41) Nucleotide Analogs (1) Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Cationic Lipids (2) Phospholipids (155) Human Pre-designed siRNA Sets (2) Polymers (1) Cytidine Nucleotide (1) siRNAs (4)

769

Inhibitors & Agonists

Fluorescent Dyes

172

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

138

Isotope-Labeled Compounds

Antibodies

Click Chemistry

203

Oligonucleotides

GMP Molecules

Targets Recommended: SnRK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13704

SN-38 Maximum Cited Publications 70 Publications Verification 7-Ethyl-10-hydroxycamptothecin	Drug Metabolite Topoisomerase ADC Payload Autophagy	Infection Cancer
SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 can bind to RPL15. SN-38 inhibits DNA and RNA synthesis with IC₅₀s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) .

HY-128946

CL2A-SN-38 5 Publications Verification	Drug-Linker Conjugates for ADC	Inflammation/Immunology Cancer
CL2A-SN-38 is a agent-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody agent conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A-SN-38 uses hydrolyzable linker to deliver active agents within tumor cells and in the tumor microenvironment, resulting in bystander effects .

HY-145010

SN-011 10+ Cited Publications	STING	Inflammation/Immunology
SN-011 is a potent and selective mouse and human STING inhibitor, with an IC₅₀ of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease .

HY-B0002B

Ondansetron 5+ Cited Publications GR 38032; SN 307	5-HT Receptor	Neurological Disease
Ondansetron (GR 38032; SN 307) is a highly selective 5-HT₃ receptor antagonist with an IC₅₀ value of 103 pM. Ondansetron exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron can inhibit nausea and vomiting induced by chemotherapy and radiotherapy .

HY-17552

sn-Glycero-3-phosphocholine 3 Publications Verification Choline Alfoscerate; Alpha-GPC; L-α-GPC	Cholinesterase (ChE) Endogenous Metabolite	Neurological Disease
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .

HY-126373

SN-38 glucuronide SN-38G	Drug Metabolite	Cancer
SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .

HY-101194

Tin protoporphyrin IX dichloride 15+ Cited Publications Tin-protoporphyrin IX; SN-Protoporphyrin; SNPPIX	Reactive Oxygen Species (ROS)	Cancer
Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model .

HY-113128A

sn-Glycerol 3-phosphate lithium	Endogenous Metabolite	Metabolic Disease
sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism .

HY-131057

Mc-VC-PAB-SN38 1 Publications Verification	Drug-Linker Conjugates for ADC	Cancer
Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-113128

sn-Glycerol 3-phosphate	Endogenous Metabolite	Metabolic Disease
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism .

HY-B0002

Ondansetron hydrochloride 5+ Cited Publications GR 38032 hydrochloride; SN 307 hydrochloride	5-HT Receptor	Neurological Disease
Ondansetron (GR 38032; SN 307) hydrochloride is a highly selective 5-HT₃ receptor antagonist with an IC₅₀ value of 103 pM. Ondansetron hydrochloride exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron hydrochloride can inhibit nausea and vomiting induced by chemotherapy and radiotherapy .

HY-13735A

Quinacrine dihydrochloride 5+ Cited Publications Mepacrine dihydrochloride; SN-390 dihydrochloride	Parasite Apoptosis Autophagy Mitophagy	Infection Cancer
Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis .

HY-13704S

SN-38-d3 NK012-d₃	Topoisomerase ADC Payload Autophagy	Cancer
SN-38-d₃ is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC₅₀s of 0.077 and 1.3 μM, respectively .

HY-P0151

SN50 40+ Cited Publications	NF-κB	Inflammation/Immunology
SN50 is a cell permeable inhibitor of NF-κB translocation.

HY-B0002A

Ondansetron hydrochloride dihydrate 5+ Cited Publications GR 38032 hydrochloride dihydrate; SN 307 hydrochloride dihydrate	5-HT Receptor	Neurological Disease
Ondansetron (GR 38032; SN 307) hydrochloride dehydrate is a highly selective 5-HT₃ receptor antagonist with an IC₅₀ value of 103 pM. Ondansetron hydrochloride dehydrate exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron hydrochloride dehydrate can inhibit nausea and vomiting induced by chemotherapy and radiotherapy .

HY-153013

SN38-COOH	Drug-Linker Conjugates for ADC	Cancer
SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis .

HY-P3229

SN52 2 Publications Verification	NF-κB	Cancer
SN52 is a potent, competitive, and cell-permeable inhibitor of NF-κB2. SN52 is a variant of the SN50 peptide and inhibits the nuclear translocation of p52-RelB heterodimers. SN52 has a strong radiosensitization effect on prostate cancer cells. SN52 can be used for cancer research .

HY-141572

1,2-Dioleoyl-sn-glycerol SN-1,2-Dioleoylglycerol; 18:1/18:1-DG	Drug Derivative	Metabolic Disease
1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol; 18:1/18:1-DG) is a glycerolipid located on the plasma membrane. 1,2-Dioleoyl-sn-glycerol consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. 1,2-Dioleoyl-sn-glycerol can induce acrosome reaction in human sperm .

HY-W140974

SN-001 1 Publications Verification	STING	Cancer
SN-001 is a STING inhibitor with an IC₅₀ of 3.82 μM .

HY-126350

CL2-SN-38 1 Publications Verification	Drug-Linker Conjugates for ADC	Cancer
CL2-SN-38 is a cleavable linker-based agent-Linker conjugate, it can conjugate with the anti-Trop-2-humanized antibody hRS7. CL2-SN-38 can be used for the reasearch of cancer .

HY-16696

SN 2 5 Publications Verification	Flavivirus Dengue Virus TRP Channel	Infection
SN 2 is a potent activator of TRPML3 ion channel with an EC₅₀ of 1.8 μM . SN 2 also acts as a potent inhibitor of Dengue virus 2 (DENV2) and Zika virus (ZIKV) .

HY-136170

MC-SN38 2 Publications Verification	Drug-Linker Conjugates for ADC	Cancer
MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks .

HY-128943

MAC glucuronide phenol-linked SN-38 1 Publications Verification	Drug-Linker Conjugates for ADC	Cancer
MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) agent linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC₅₀ values of 113 and 67 ng/mL, respectively.Albumin-coupled MAC glucosidol-linked SN-38 shows good stability in mouse plasma .

HY-13704R

SN-38 (Standard) 7-Ethyl-10-hydroxycamptothecin (Standard)	Drug Metabolite Reference Standards Topoisomerase ADC Payload Autophagy	Cancer
SN-38 (Standard) is the analytical standard of SN-38. This product is intended for research and analytical applications. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) .

HY-139909A

CL2E-SN38 TFA 1 Publications Verification	Drug-Linker Conjugates for ADC	Cancer
CL2E-SN-38 TFA, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor .

HY-164668

ADC Control Human IgG1-SN-38	Antibody-Drug Conjugates (ADCs)	Cancer
ADC Control Human IgG1-SN-38 is an isotype control of ADC Human IgG1-SN-38. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946).

HY-107658

SN 6 5+ Cited Publications	Na+/Ca2+ Exchanger	Cardiovascular Disease
SN 6 is a selective Na ⁺/Ca ²⁺ exchanger (NCX) inhibitor, and inhibits ⁴⁵Ca ²⁺ uptake by NCX1, NCX2, and NCX3, with IC₅₀s of 2.9, 16, and 8.6 μM, respectively.

HY-13735B

Quinacrine hydrochloride hydrate 5+ Cited Publications Mepacrine hydrochloride hydrate; SN-390 hydrochloride hydrate	Parasite Apoptosis Autophagy Mitophagy	Infection Cancer
Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis .

HY-W040185

1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium 1,2-DPPA sodium; PA(14:0/14:0) sodium; 1,2-Dimyristoyl-SN-glycero-3-phosphate sodium	Liposome	Metabolic Disease
1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium is a phospholipid containing the long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.

HY-112552

1,2-Distearoyl-sn-glycerol DSG; 1,2-Dioctadecanoyl-SN-glycerol	Endogenous Metabolite Biochemical Assay Reagents	Others
1,2-Distearoyl-sn-glycerol (DSG) is a glyceride compound. 1,2-Distearoyl-sn-glycerol can be used as an internal standard for the analysis of molecular species of diacylglycerol (DAG) and other phospholipids in rat brain .

HY-146242

SN05	EAAT ASCT	Cancer
SN05 is a potent amino acid transport (AAT) inhibitor with K_i values of 2.77 μM, 0.73 μM, 0.87 μM, 3.7 μM, 7.25 μM, 7.23 μM and 2.22 μM for hASCT1, rASCT2, hASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN05 can be used in the study of cancer .

HY-153962

SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3	Drug-Linker Conjugates for ADC	Cancer
SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a Drug-Linker Conjugate for ADC. SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 consists of the anti-cancer agent SN38 (HY-13704) and a linker Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 (HY-131157). SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 can be used for synthesis of ADCs . SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-145009

SN-008	STING	Others
SN-008, a less active SN-011 analog, can be used as a negative control .

HY-159563

Mal-va-mac-SN38	Drug-Linker Conjugates for ADC	Cancer
Mal-va-mac-SN38 is a drug-linker conjugate for ADC. Mal-va-mac-SN38 contains a ADC cytotoxin SN-38 (HY-13704) and a linker (HY-126364). Mal-va-mac-SN38 can rapidly and covalently bind with endogenous albumin in vivo, resulting in the formation of HSA-va-mac-SN38. Mal-va-mac-SN38 demonstrates exceptional stability in human plasma, and has anti-tumor and anti-metastasis effect .

HY-W704966

2-Stearoyl-sn-glycero-3-phosphocholine	Endogenous Metabolite	Metabolic Disease
2-Stearoyl-sn-glycero-3-PC is a lysophospholipid that contains stearic acid (HY-B2219) at the sn-2 position. It has been found in rabbit myocardium.

HY-W440981

SPPC 1-Stearoyl-2-palmitoyl-SN-glycero-3-phosphocholine	Liposome	Cancer
SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).

HY-W777986

1-Eicosapentaenoyl-sn-glycerol-3-phosphocholine 1-EPA-2-OH-SN-glycerol-3-phosphocholine	Drug Derivative	Metabolic Disease
1-Eicosapentaenoyl-sn-glycerol-3-phosphocholine (1-EPA-2-OH-sn-glycerol-3-phosphocholine) is an ester product.

HY-113128S

sn-Glycerol 3-phosphate-13C3 disodium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
sn-Glycerol 3-phosphate- ¹³C₃ disodium is the ¹³C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .

HY-17552R

sn-Glycero-3-phosphocholine (Standard) Choline Alfoscerate (Standard); Alpha-GPC (Standard); L-α-GPC (Standard)	Reference Standards Cholinesterase (ChE) Endogenous Metabolite	Neurological Disease
sn-Glycero-3-phosphocholine (Standard) is the analytical standard of sn-Glycero-3-phosphocholine. This product is intended for research and analytical applications. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].

HY-14572

PR-104A SN 27858	DNA Alkylator/Crosslinker Drug Metabolite	Cancer
PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity . PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL) .

HY-126373S1

SN-38 glucuronide-13C6 SN-38G-¹³C₆	Isotope-Labeled Compounds	Others
SN-38 glucuronide- ¹³C₆ is the ¹³C labeled SN-38 glucuronide (HY-126373) . SN-38 glucuronide is an inactive metabolite of the cancer agent Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .

HY-116170

SN34037	Aldose Reductase	Cancer
SN34037 is a specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) with the ability to inhibit the cytotoxic activity of PR-104A. SN34037-sensitive coumberone reduction provides a rapid and specific assay for AKR1C3 activity. SN34037 inhibits the aerobic cytotoxicity of PR-104A in TF1 erythroleukemia cells with high AKR1C3 expression, but not in Nalm6 pre-B acute lymphoblastic leukemia cells with low AKR1C3 expression .

HY-141574

1,2-Didecanoyl-Sn-glycerol	PKC	Others
1,2-Didecanoyl-sn-glycerol is an analog of the PKC-activating second messenger DAG. Although the biological activities of 1,2-didecanoyl-sn-glycerol have not been well characterized, it is expected to behave similarly to 1,2-dioctanoyl-sn-glycerol.

HY-B0002BS

Ondansetron-d5 GR 38032-d₅; SN 307-d₅	5-HT Receptor Isotope-Labeled Compounds	Neurological Disease
Ondansetron-d₅ is the deuterium labeled Ondansetron (HY-B0002B). Ondansetron (GR 38032; SN 307) is a highly selective 5-HT₃ receptor antagonist with an IC₅₀ value of 103 pM. Ondansetron exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron can inhibit nausea and vomiting induced by chemotherapy and radiotherapy .

HY-138815

(S)-N-(1H-Indole-3-acetyl)tryptophan	Glycosidase	Metabolic Disease
(S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a Tryptophan derivative that weakly inhibits β-D-glucosidase .

HY-117168

1,2-Dilinoleoyl-sn-glycerol	Endogenous Metabolite	Metabolic Disease
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (HY-N0729) (18:2) side chains attached at both the sn-1 and sn-2 positions . 1,2-Dilinoleoyl-sn-glycerol can be prepared from L-dilinoleoylphosphatidylcholine via hydrolysis with phospholipase C .

HY-139909

CL2E-SN38	Drug-Linker Conjugates for ADC	Cancer
CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor .

HY-145767A

SN-38-CO-DMEDA TFA	Drug Intermediate	Others
SN-38-CO-DMEDA TFA is the intermediate product for synthesizing antibody-conjugated drug LND1035 .

HY-123849

SN32976	PI3K mTOR	Cancer
SN32976 is a potent and selective class I PI3K and mTOR inhibitor with IC₅₀s of 15.1 nM, 461 nM, 110 nM, 134 nM and 194 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ and mTOR, respectively. SN32976 shows high selectivity among other 442 kinases. SN32976 shows anticancer effects .

HY-117115

1,2-Dihexanoyl-sn-glycerol	Biochemical Assay Reagents	Others
1,2-Dihexanoyl-sn-glycerol is an analog of protein kinase C (PKC) that activates the second messenger diacylglycerol (DAG). Although the biological activity of 1,2-dicaproyl-sn-glycerol has not been well characterized, it is expected to behave similarly to 1,2-dioctanoyl-sn-glycerol.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13704

SN-38 Maximum Cited Publications 70 Publications Verification 7-Ethyl-10-hydroxycamptothecin	Alkaloids Structural Classification Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Quinoline Alkaloids Plants Disease Research Fields Source Classification Cancer	Drug Metabolite Topoisomerase ADC Payload Autophagy
SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 can bind to RPL15. SN-38 inhibits DNA and RNA synthesis with IC₅₀s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) .

HY-113424A

1,2-Dioleoyl-sn-glycero-3-phosphocholine 5+ Cited Publications DOPC	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Liposome Endogenous Metabolite
1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.

HY-130462

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC 3 Publications Verification POPC	Structural Classification Microorganisms Classification of Application Fields Other Diseases Plants Disease Research Fields Lipid Source Classification	Liposome
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .

HY-112530

1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine DSPE	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Lipid Source Classification	Liposome Endogenous Metabolite
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes .

HY-17552

sn-Glycero-3-phosphocholine 3 Publications Verification Choline Alfoscerate; Alpha-GPC; L-α-GPC	Natural Products Microorganisms Endogenous metabolite Source Classification	Cholinesterase (ChE) Endogenous Metabolite
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .

HY-A0210

Cerulenin 10+ Cited Publications	Microorganisms Antifungal Classification of Application Fields Antibiotics Metabolic Disease Mammalian Cell Culture Disease Research Anticancer Disease Research Fields Other Antibiotics Source Classification	Fatty Acid Synthase (FASN) Fungal Apoptosis Antibiotic
Cerulenin, a potent, natural inhibitor of fatty acid synthase (FASN), is an epoxide produced by the fungus Cephalosporium caeruleus. Cerulenin inhibits topoisomerase I catalytic activity and augments SN-38-induced apoptosis. Cerulenin has antifungal and antitumor activies .

HY-125783

1-Palmitoyl-sn-glycero-3-phosphocholine 2 Publications Verification 16:0 Lyso PC	Infection Structural Classification Classification of Application Fields Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Lipid	Endogenous Metabolite
1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .

HY-111832

1,2,3,6-Tetragalloylglucose TeGG	other families Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	UGT
1,2,3,6-Tetragalloylglucose (TEgG) is a competitive inhibitor of UDP-glucuronyltransferase UGT1A1, targeting the competitive substrate binding site of UGT1A1. 1,2,3,6-Tetragalloylglucose inhibits UGT1A1-mediated β-estradiol 3-glucuronidation and SN-38 glucuronidation with IC₅₀ of 6.01 μM and 4.31 μM, respectively, and binds to UGT1A1 with K_i of 3.55 μM. 1,2,3,6-Tetragalloylglucose also induces tumor cell apoptosis, inhibit cell proliferation, activates caspase-3 and induces DNA fragmentation in HL-60 cells. 1,2,3,6-Tetragalloylglucose also inhibits HIV integrase and reverse transcriptase, and inhibits HCV protease .

HY-113128A

sn-Glycerol 3-phosphate lithium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism .

HY-N9410

Lysophosphatidylcholine 18:2 1-Linoleoyl-2-Hydroxy-SN-glycero-3-PC; LPC(18:2/0:0); LysoPC(18:2)	Infection Structural Classification Natural Products Classification of Application Fields Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). Low plasma Lysophosphatidylcholine 18:2 also has been shown to predict impaired glucose tolerance, insulin resistance, type 2 diabetes, coronary artery disease, and memory impairment .

HY-113128

sn-Glycerol 3-phosphate	Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism .

HY-125771

1-Stearoyl-sn-glycero-3-phosphocholine 18:0 Lyso-PC; LPC(18:0)	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite HDAC STAT Apoptosis
1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells .

HY-W040268

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Lipid Source Classification	Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane .

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-SN-glycero-3-phosphatidylcholine	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-113010

1-Arachidoyl-sn-glycero-3-phosphocholine	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).

HY-131897

1-Stearoyl-2-arachidonoyl-sn-glycerol 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Lipid Source Classification	PKC TRP Channel Endogenous Metabolite
1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity .

HY-113128C

(Rac)-sn-Glycerol 3-phosphate DL-α-Glycerol phosphate	Structural Classification Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Lipid Source Classification	Endogenous Metabolite
(Rac)-sn-Glycerol 3-phosphate is an a-site substrate analogue. (Rac)-sn-Glycerol 3-phosphate is bound to the a-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited .

HY-134200

1-Palmitoyl-2-oleoyl-sn-glycerol	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1-Palmitoyl-2-oleoyl-sn-glycerol is a diacylglycerol hormogonium inducer that can be isolated from the coralloid roots of Cycas revoluta. 1-Palmitoyl-2-oleoyl-sn-glycerol promotes the differentiation of filamentous Nostoc cell aggregates into motile hormogonia, and further induces the formation of dense bundle-like structures. 1-Palmitoyl-2-oleoyl-sn-glycerol is not only commonly used as a diacylglycerol standard, but also can effectively identify and separate glycerophosphate-containing phospholipid enantiomers after acetylation. 1-Palmitoyl-2-oleoyl-sn-glycerol is also used to study cyanobacterial developmental mechanisms and lipid analysis .

HY-13704R

SN-38 (Standard) 7-Ethyl-10-hydroxycamptothecin (Standard)	Alkaloids Labiatae Samanea saman (Jacq.) Merr. Quinoline Alkaloids Plants Source Classification	Drug Metabolite Reference Standards Topoisomerase ADC Payload Autophagy
SN-38 (Standard) is the analytical standard of SN-38. This product is intended for research and analytical applications. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) .

HY-126356

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Lipid Source Classification	Liposome
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is a major phospholipid in low-density lipoprotein and belongs to the group of 1-acyl phosphatidylcholines. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine does not induce morphological changes in washed human platelets. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine can be used for the research of atherosclerosis and thrombotic diseases .

HY-113437A

1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite . It is used in the generation of micelles, liposomes, and artificial membranes.

HY-W011309A

1-O-Hexadecyl-sn-glycerol (S)-1-O-HDG; (S)-HXDG	Natural Products Marine natural products Sponge Source Classification	PPAR
1-O-Hexadecyl-sn-glycerol [(S)-HXDG] is an alkyl glycerol monoether derived from T. aurantia .

HY-W337335

1-Palmitoyl-sn-glycerol 3-phosphate sodium salt 1-P-GPA sodium salt	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Liposome
Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) sodium salt is a type of phospholipid and a precursor of lipid membranes. 1-Palmitoyl-sn-glycerol 3-phosphate sodium salt can be incorporated into POPC liposomes, resulting in significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate sodium salt can induce platelet aggregation, but its activity is 30 times lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate .

HY-108776

(Rac)-sn-Glycerol 3-phosphate sodium DL-α-Glycerol phosphate sodium	Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
(Rac)-sn-Glycerol 3-phosphate sodium is an a-site substrate analogue. (Rac)-sn-Glycerol 3-phosphate sodium is bound to the a-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited .

HY-W019833

MSPC PC(14:0/18:0); 1-Myristoyl-2-stearoyl-SN-glycero-3-phosphocholine	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.

HY-126359

1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine SLPC; 18:0-18:2 PC	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Lipid Source Classification	Endogenous Metabolite
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine (SLPC; 18:0-18:2 PC) is an endogenous phospholipid marker molecule in the glycerophospholipid metabolic pathway. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a core component of the phospholipid bilayer of biological membranes and a key responsive lipid for radiation injury and cardiometabolic diseases. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine constitutes the phospholipid bilayers of cell membranes and high-density lipoprotein (HDL), and regulates the core activity of lipoprotein functional homeostasis. The content of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine in mouse serum shows a significant dose-dependent decrease with increasing ionizing radiation dose, and its level in human HDL also decreases significantly in metabolic syndrome. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can serve as a biological dosimeter marker for ionizing radiation injury, and is used for rapid and accurate assessment of radiation absorbed dose in exposed individuals. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can also act as a lipidomics research target for cardiometabolic diseases such as lipid metabolic syndrome and early-onset coronary heart disease .

HY-112552

1,2-Distearoyl-sn-glycerol DSG; 1,2-Dioctadecanoyl-SN-glycerol	Structural Classification Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Lipid Source Classification	Endogenous Metabolite Biochemical Assay Reagents
1,2-Distearoyl-sn-glycerol (DSG) is a glyceride compound. 1,2-Distearoyl-sn-glycerol can be used as an internal standard for the analysis of molecular species of diacylglycerol (DAG) and other phospholipids in rat brain .

HY-W010736

1,2-Dipalmitoyl-sn-glycerol	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycerol is an endogenous metabolite.

HY-141616

1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine	Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine is an endogenous metabolite present in Blood that can be used for the research of Pregnancy and Sepsis .

HY-157647

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC PC(18:0/22:4)	Structural Classification Endogenous metabolite Lipid Source Classification	CDK Apoptosis
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) is an inhibitor of cyclin-dependent kinases (CDKs). 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC induces apoptosis and inhibits the growth of various cancer cell lines .

HY-17552R

sn-Glycero-3-phosphocholine (Standard) Choline Alfoscerate (Standard); Alpha-GPC (Standard); L-α-GPC (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite Source Classification	Reference Standards Cholinesterase (ChE) Endogenous Metabolite
sn-Glycero-3-phosphocholine (Standard) is the analytical standard of sn-Glycero-3-phosphocholine. This product is intended for research and analytical applications. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].

HY-126967A

1-Palmitoyl-sn-glycerol 3-phosphate 1-P-GPA	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Liposome
1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is a phospholipid and lipid membrane precursor. 1-Palmitoyl-sn-glycerol 3-phosphate integrates into POPC liposomes, causing significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate induces platelet aggregation, but its activity is 30-fold lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate .

HY-130462R

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Standard) POPC (Standard)	Structural Classification Natural Products Microorganisms Plants Source Classification	Liposome Reference Standards
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Standard) is the analytical standard of 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. This product is intended for research and analytical applications. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .

HY-W440982A

(Rac)-SOPC (Rac)-PC(18:0/18:1); (Rac)-2-Oleoyl-1-stearoyl-SN-glycero-3-phosphocholine	Structural Classification Animals Lipid Source Classification	Liposome
(Rac)-SOPC ((Rac)-PC(18:0/18:1)) ((Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine) is the racemate of SOPC (HY-W440982). SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can stabilize the outer segment membrane of frog rods .

HY-W127369

1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine PC(O-16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine is an endogenous metabolite present in Urine that can be used for the research of Obesity .

HY-N11604

1-(1(Z)-Hexadecenyl)-2-palmitoleoyl-sn-glycero-3-phosphocholine C16(Plasm)-16:1-PC; PC(P-16:0/16:1); PlsC 16:0/16:1	Structural Classification Animals Lipid Source Classification	Biochemical Assay Reagents
1-(1(Z)-Hexadecenyl)-2-palmitoleoyl-sn-glycero-3-phosphocholine [PC (P-16:0/16:1 (9Z))] is a phosphatidylcholine that can be utilized for liposome preparation and serves as a marker in metabolomics research .

HY-118442

Sphingosine (d14:1) Tetradecasphing-4-enine	Structural Classification Animals Classification of Application Fields Disease Research Fields Lipid Source Classification Cancer	PKC
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters .

HY-113128B

sn-Glycerol 3-phosphate biscyclohexylammonium salt	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate biscyclohexylammonium salt is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate biscyclohexylammonium salt from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate biscyclohexylammonium salt for lipid metabolism .

HY-N9444

1,3-Dipalmitoyl-2-linoleoylglycerol Triglyceride PLP,SN	Malvaceae Structural Classification Pseudobombax munguba (Mart.) Dugand Plants Lipid Source Classification	Endogenous Metabolite
1,3-Dipalmitoyl-2-linoleoyl glycerol is a triacylglycerol that contains Palmitic acid at the sn-1 and sn-3 positions and Linoleic acid.

HY-125783R

1-Palmitoyl-sn-glycero-3-phosphocholine (Standard) 16:0 Lyso PC (Standard)	Infection Structural Classification Natural Products Disease markers Endogenous metabolite	Endogenous Metabolite Reference Standards
1-Palmitoyl-sn-glycero-3-phosphocholine (Standard) (16:0 Lyso PC (Standard)) is the analytical standard of 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). This product is intended for research and analytical applications. 1-Palmitoyl-sn-glycero-3-phosphocholine is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .

HY-N15913

ent-DOPC	Lipid	Drug Isomer
ent-DOPC is a glycerol chirality isomer of 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) (HY-113424A) .

HY-145751

7α-Hydroxy-DHEA 7α-Hydroxydehydroepiandrosterone; 3β,7α-Dihydroxy-Δ5-androsten-17-one	Endogenous metabolite Steroids Source Classification	Cytochrome P450 Mitochondrial Metabolism
7α-Hydroxy-DHEA (7α-Hydroxydehydroepiandrosterone) is a 7α-hydroxylated metabolite of DHEA (HY-14650), catalyzed by intracellular steroid 7α-hydroxylases such as P450 2A1. 7α-Hydroxy-DHEA exhibits biological activity comparable to DHEA but does not convert into compounds with androgenic or estrogenic activity. It induces the activity of thermogenic enzymes such as mitochondrial sn-glycerol-3-phosphate dehydrogenase and cytosolic malic enzyme, enhancing heat production and reducing food utilization efficiency. As a more efficient and safer metabolite compared to DHEA, 7α-Hydroxy-DHEA holds potential for studies in the fields of obesity, metabolic diseases, and adrenal carcinoma .

HY-167885

SN-35210 free base	Flavonoids Labiatae Cynara scolymus L. Plants Source Classification	iGluR
SN-35210 free base, an ester analogue, is designed for rapid offset via esterase-mediated hydrolysis .

HY-N15340

1-Oleoyl-2-linoleoyl-sn-glycerol	Natural Products Endogenous metabolite Source Classification	PKC
1-Oleoyl-2-linoleoyl-sn-glycerol is a diacylglycerol (DG). 1-Oleoyl-2-linoleoyl-sn-glycerol can activate protein kinase C (PKC), thus triggering downstream signaling cascades and promoting tumor growth. 1-Oleoyl-2-linoleoyl-sn-glycerol is promising for research of breast cancer .

HY-W010736R

1,2-Dipalmitoyl-sn-glycerol (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycerol is an endogenous metabolite.

HY-113437

1,2-Dipalmitoyl-sn-glycerol 3-phosphate	Structural Classification Natural Products Microorganisms Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycerol 3-phosphate (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite .

HY-N16369

1,2-Di-(9Z-hexadecenoyl)-sn-glycerol	Microorganisms Antibiotics Other Antibiotics Source Classification	Thrombin
1,2-Di-(9Z-hexadecenoyl)-sn-glycerol (Compound 2e) is a diacylglycerol derivative that can be isolated from the fungus Stereum Hirsutum. 1,2-Di-(9Z-hexadecenoyl)-sn-glycerol has potential thrombin-inhibiting activity and can be used in research related to antithrombotic drugs .

HY-W040193B

(S)-DSPC (S)-1,2-Distearoyl-SN-glycero-3-PC; (S)-1,2-Distearoyl-SN-glycero-3-phosphorylcholine	Lipid	Liposome
(S)-DSPC ((S)-1,2-Distearoyl-sn-glycero-3-PC) is a (S)-enantiomer of DSPC (HY-W040193).

HY-N15353

1-Palmitoyl-2-linoleoyl-sn-glycerol	Structural Classification Plants Cycadaceae Cycas revoluta Thunb. Lipid Source Classification	Bacterial
1-Palmitoyl-2-linoleoyl-sn-glycerol is a diacylglycerol (DAG)-type lipid signaling molecule found in the coralloid roots of Cycas revoluta, and serves as a major active component of the plant-secreted hormogonium-inducing factor (HIF). At a concentration of 1 nmol/disc (approximately 0.6 µg), 1-palmitoyl-2-linoleoyl-sn-glycerol can significantly induce the differentiation of filamentous aggregates of Nostoc into motile hormogonia, thereby promoting chemotaxis toward host roots and the establishment of symbiosis. This compound holds significant research and application potential in areas such as plant–microbe interactions, rhizosphere signaling pathways, and nitrogen-fixing symbiosis .

HY-N16283

Ent-DSPE 2,3-Distearoyl-SN-glycero-1-phosphoethanolamine	Lipid	Biochemical Assay Reagents
Ent-DSPE is an enantiomer of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) (HY-112530). Ent-DSPE can be used to prepare lipid nanoparticles for drug delivery .

Cat. No.	Product Name	Chemical Structure

HY-13704S

SN-38-d3
SN-38-d₃ is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC₅₀s of 0.077 and 1.3 μM, respectively .

HY-W040193S

DSPC-d70
DSPC-d₇₀ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₀) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-W040193S3

DSPC-d83
DSPC-d₈₃ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₈₃) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-146794S

1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphocholine-d7
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphocholine-d₇ is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphocholine.

HY-146798S

1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine-d7
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine-d₇ is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine.

HY-113128S

sn-Glycerol 3-phosphate-13C3 disodium
sn-Glycerol 3-phosphate- ¹³C₃ disodium is the ¹³C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .

HY-113424AS

1,2-Dioleoyl-sn-glycero-3-phosphocholine-d9
1,2-Dioleoyl-sn-glycero-3-phosphocholine-d₉ is deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phosphocholine. 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelle

HY-130462S

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d31
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d₃₁ is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for

HY-126373S1

SN-38 glucuronide-13C6
SN-38 glucuronide- ¹³C₆ is the ¹³C labeled SN-38 glucuronide (HY-126373) . SN-38 glucuronide is an inactive metabolite of the cancer agent Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .

HY-125783S1

1-Palmitoyl-sn-glycero-3-phosphocholine-d31

1-Palmitoyl-sn-glycero-3-phosphocholine-d₃₁ (16:0 Lyso PC-d₃₁) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .

HY-B0002BS

Ondansetron-d5

Ondansetron-d₅ is the deuterium labeled Ondansetron (HY-B0002B). Ondansetron (GR 38032; SN 307) is a highly selective 5-HT₃ receptor antagonist with an IC₅₀ value of 103 pM. Ondansetron exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron can inhibit nausea and vomiting induced by chemotherapy and radiotherapy .

HY-139931S

1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC
1-Stearoyl-2-Arachidonoyl-d₈-sn-glycero-3-PC is the deuterium labeled 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC .

HY-125783S3

1-Palmitoyl-sn-glycero-3-phosphocholine-d9-1

1-Palmitoyl-sn-glycero-3-phosphocholine-d₉-1 (16:0 Lyso PC-d₉-1) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .

HY-17552S

sn-Glycero-3-phosphocholine-d9

sn-Glycero-3-phosphocholine-d₉ is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .

HY-113437AS

1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium
1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d₆₂ (sodium) is deuterium labeled 1,2-Dipalmitoyl-sn-glycerol 3-phosphate. 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite .

HY-W019999

1,2-Dimyristoyl-d54-sn-glycero-3-phosphocholine
1,2-Dimyristoyl-d₅₄-sn-glycero-3-phosphocholine is the deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine.

HY-146833S

1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine-d7
1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine-d₇ is deuterium labeled 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine.

HY-W140439S1

1-Oleoyl-sn-glycero-3-phosphocholine-d7
1-Oleoyl-sn-glycero-3-phosphocholine-d₇ is deuterium labeled L-Alpha-Lysophosphatidylcholine,oleoyl.

HY-B0002S1

Ondansetron-d6 hydrochloride
Ondansetron-d₆ (hydrochloride) is the deuterium labeled Ondansetron hydrochloride . Ondansetron hydrochloride is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy .

HY-W653919

SN-38 glucuronide-d3
SN-38 glucuronide-d₃ is deuterium labeled SN-38 glucuronide. SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .

HY-W010736S

1,2-Dipalmitoyl-sn-glycerol-d9
1,2-Dipalmitoyl-sn-glycerol-d9 is a deuterated labeled 1,2-Dipalmitoyl-sn-glycerol . 1,2-Dipalmitoyl-sn-glycerol is an endogenous metabolite.

HY-125940S

DPPG-d62
DPPG-d₆₂ (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l

HY-131897S

1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol
1-Stearoyl-2-Arachidonoyl-d₈-sn-Glycerol is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycerol. 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity .

HY-115415S

1,2-Distearoyl-sn-glycero-3-phosphate-d70 sodium
1,2-Distearoyl-sn-glycero-3-phosphate-d₇₀ (sodium) is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphate.

HY-W013063S

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d11
1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d₁₁ is a deuterium labeled 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine (HY-W013063). 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine is a phospholipid. 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine can be used for obesity research .

HY-145742S

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-d70 sodium
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-d₇₀ (sodium) is deuterium labeled 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is the component of liposomes for drug delivery .

HY-W127457S

1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d22
1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d₂₂ is deuterium labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine.

HY-W040268S1

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d9
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d₉ is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane .

HY-W040268S

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d62
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d₆₂ is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane .

HY-126356S

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d11

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d₁₁ is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (HY-126356). 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is a major phospholipid in low-density lipoprotein and belongs to the group of 1-acyl phosphatidylcholines. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine does not induce morphological changes in washed human platelets. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine can be used for the research of atherosclerosis and thrombotic diseases .

HY-146894S

DSPC-d35
1-Stearoyl-2-stearoyl-sn-glycero-3-phosphocholine-d₃₅ is deuterium labeled 1-Stearoyl-2-stearoyl-sn-glycero-3-phosphocholine.

HY-141617S

1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE
1-Palmitoyl-d₉-2-hydroxy-sn-glycero-3-PE is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE .

HY-141616S

1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine-d5
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine-d₅ is deuterium labeled 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine.

HY-146785S

1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate-13C16 sodium
1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate- ¹³C₁₆ (sodium) is ¹³C₁₆ labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate.

HY-143675S

1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS-d9
1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS-d₉ is the deuterium labeled 1-Palmitoyl-2-palmitoyl-sn-glycero-3-PS .

HY-143670S

1-Palmitoyl-2-arachidonoyl-3-palmitoyl-sn-glycerol-d9
1-Palmitoyl-2-arachidonoyl-3-palmitoyl-sn-glycerol-d₉ is the deuterium labeled 1-Palmitoyl-2-arachidonoyl-3-palmitoyl-sn-glycerol .

HY-112530S

1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d70
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d₇₀ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis

HY-146875S

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol-d31 ammonium
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol-d₃₁ (ammonium) is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium).

HY-146825S

1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoinositol-d7 ammonium
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoinositol-d₇ (ammonium) is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium).

HY-125783S2

1-Palmitoyl-sn-glycero-3-phosphocholine-d49

1-Palmitoyl-sn-glycero-3-phosphocholine-d₄₉ (16:0 Lyso PC-d₄₉) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .

HY-125783S

1-Palmitoyl-sn-glycero-3-phosphocholine-d9
1-Palmitoyl-sn-glycero-3-phosphocholine-d₉ (16:0 Lyso PC-d₉) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .

HY-146820S

1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d7 sodium
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d₇ (sodium) is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium).

HY-146864S

1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium
1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-146861S

1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium
1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-146865S

1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-130462S1

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d₈₂ is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for

HY-146869S

1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d5 sodium
1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146870S

1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine-d5 sodium
1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146866S

1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d5 sodium
1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-158947S

1-1(Z)-Hexadecenyl-2-Palmitoyl-d9-sn-glycero-3-PE
1-1(Z)-Hexadecenyl-2-Palmitoyl-d₉-sn-glycero-3-PE is deuterium labeled 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE .

Targets Recommended: SnRK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W040193GL

DSPC (GMP Like) 1,2-Distearoyl-SN-glycero-3-PC (GMP Like); 1,2-Distearoyl-SN-glycero-3-phosphorylcholine (GMP Like)	Liposome	Others
DSPC (GMP Like) (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is DSPC (HY-W040193) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-112005G

DOPE Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-SN-glycero-3-phosphoethanolamine	Ferroptosis Glutathione Peroxidase ACSL Family Amino acid Transporter	Neurological Disease Inflammation/Immunology
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .

HY-107614G

1-Oleoyl lysophosphatidic acid sodium 1-Oleoyl-SN-glycero-3-phosphate sodium; 1-Oleoyl-LPA sodium	LPL Receptor ROCK TGF-beta/Smad TGF-β Receptor	Neurological Disease Cancer
1-Oleoyl lysophosphatidic acid sodium (GMP) is the GMP-grade form of 1-Oleoyl lysophosphatidic acid sodium (HY-107614). GMP-grade small molecules serve as auxiliary reagents in cell therapy. 1-Oleoyl lysophosphatidic acid sodium is a bioactive lipid signaling molecule. 1-Oleoyl lysophosphatidic acid sodium inhibits lysoPLD-catalyzed hydrolysis of lysophosphatidylcholine and FS-3. 1-Oleoyl lysophosphatidic acid sodium activates LPA₁ and LPA₂, thereby triggering calcium mobilization, NFATc1 translocation, Rho/ROCK activation, Smad2/3 phosphorylation and c-Fos expression. 1-Oleoyl lysophosphatidic acid sodium induces anxiety-like, depression-like and hypoactivity phenotypes, regulates osteoclast cytoskeleton and viability, reduces osteoclast bone resorptive activity, and drives mesenchymal stem cell differentiation into myofibroblast-like cells. 1-Oleoyl lysophosphatidic acid sodium stimulates the secretion of transforming growth factor-β1 and stromal cell-derived factor-1. 1-Oleoyl lysophosphatidic acid sodium is applicable to research related to anxiety, depression and ovarian cancer .

HY-112005GL

DOPE (GMP Like) Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-SN-glycero-3-phosphoethanolamine (GMP Like)	Liposome Endogenous Metabolite	Inflammation/Immunology
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks