99614-02-5
99614-02-5
Chemical Structure
Ondansetron
Synonym(s): GR 38032; SN 307
- CAS No.: 99614-02-5
- Formula:C18H19N3O
- Molecular Weight:293.36
IUPAC Name: 9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-1,2,3,9-tetrahydro-4H-carbazol-4-one
InChIKey: FELGMEQIXOGIFQ-UHFFFAOYSA-N
SMILES: O=C1C(CN2C=CN=C2C)CCC(N3C)=C1C4=C3C=CC=C4
Biological Activity: Ondansetron (GR 38032) is a selective 5-HT3 receptor antagonist. Ondansetron inhibits nausea and vomiting. Ondansetron can be used in research on chemotherapy-induced nausea and vomiting[1][2].
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Ondansetron | 99.40% | Ondansetron (GR 38032) is a selective 5-HT3 receptor antagonist. Ondansetron inhibits nausea and vomiting. Ondansetron can be used in research on chemotherapy-induced nausea and vomiting. | ||||||||||||||||||||
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Ondansetron (Standard) | 99.28% | Ondansetron (Standard) (GR 38032 (Standard); SN 307 (Standard)) is the analytical standard of Ondansetron (HY-B0002B). This product is intended for research and analytical applications. Ondansetron (GR 38032) is a selective 5-HT3 receptor antagonist. Ondansetron inhibits nausea and vomiting. Ondansetron can be used in research on chemotherapy-induced nausea and vomiting. | ||||||||||||||||||||
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Ondansetron-d3 | Ondansetron-d3 (GR 38032-d3; SN 307-d3) is the deuterated-labeled Ondansetron (HY-B0002B). Ondansetron (GR 38032) is a selective 5-HT3 receptor antagonist. Ondansetron inhibits nausea and vomiting. Ondansetron can be used in research on chemotherapy-induced nausea and vomiting. | |||||||||||||||||||||
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Ondansetron-13C,d3 | Ondansetron-13C,d3 (GR 38032-13C,d3; SN 307-13C,d3) is the deuterated, 13C-labeled Ondansetron (HY-B0002B). Ondansetron (GR 38032) is a selective 5-HT3 receptor antagonist. Ondansetron inhibits nausea and vomiting. Ondansetron can be used in research on chemotherapy-induced nausea and vomiting. | |||||||||||||||||||||
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Ondansetron-d5 | 99% | Ondansetron-d5 (GR 38032-d5; SN 307-d5) is the deuterated-labeled Ondansetron (HY-B0002B). Ondansetron (GR 38032) is a selective 5-HT3 receptor antagonist. Ondansetron inhibits nausea and vomiting. Ondansetron can be used in research on chemotherapy-induced nausea and vomiting. | ||||||||||||||||||||
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Ondansetron-d3 hydrochloride | 98.78% | Ondansetron-d3 hydrochloride is the deuterated-labeled Ondansetron hydrochloride (HY-B0002). Ondansetron hydrochloride (GR 38032 hydrochloride) is a selective 5-HT3 receptor antagonist. Ondansetron hydrochloride inhibits nausea and vomiting. Ondansetron hydrochloride can be used in research on chemotherapy-induced nausea and vomiting. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-B0002Ondansetron hydrochloride -
Similarity Score 0.96
HY-B0002AROndansetron hydrochloride dihydrate (Standard) -
Similarity Score 0.82
HY-Z7887Ondansetron impurity 2 -
Similarity Score 0.76
HY-Z7888Ondansetron impurity 3 -
Similarity Score 0.70
HY-105109Cilansetron -
Similarity Score 0.70
HY-105109B(S)-Cilansetron -
Similarity Score 0.70
HY-U003225-HT3 antagonist 3 -
Similarity Score 0.68
HY-B0002S1Ondansetron-d6 hydrochloride -
Similarity Score 0.61
HY-W330838Ondansetron impurity 4 -
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References
- [1]. U.S. Food and Drug Administration. ZOFRAN (ondansetron hydrochloride) Injection: Prescribing Information[EB/OL]. (2004)
- [2]. Ammar HO, et al. Transdermal Delivery of Ondansetron Hydrochloride via Bilosomal Systems: In Vitro, Ex Vivo, and In Vivo Characterization Studies. AAPS PharmSciTech. 2018 Jul;19(5):2276-2287.
