2249435-90-1
2249435-90-1
Chemical Structure
SN-011
- CAS No.: 2249435-90-1
- Formula:C25H19FN2O4S
- Molecular Weight:462.49
IUPAC Name: N-(3-((4-fluorophenyl)sulfonamido)-4-hydroxyphenyl)-[1,1'-biphenyl]-4-carboxamide
InChIKey: GPXQUPCJIJBXHJ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC3=CC=C(C(NS(=O)(C4=CC=C(C=C4)F)=O)=C3)O
Biological Activity: SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SN-011 | 99.94% | SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease. | ||||||||||||||||||||
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SN-011 (Standard) | ≥98% | SN-011 (Standard) is the analytical standard of SN-011 (HY-145010). This product is intended for research and analytical applications. SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocKing CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease. | ||||||||||||||||||||
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