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Results for "

STING-associated vasculopathy with onset in infancy

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175167
    diABZI-i

    		STING IFNAR Inflammation/Immunology
    diABZI-i is an orthogonal STING inhibitor. diABZI-i significantly inhibits cGAMP-induced IFNβ in PBMCs. diABZI-i also activates constitutive signaling of V155M SAVI and exerts potent agonistic effects in the STING V155M THP-1 cell model. diABZI-i can be used for research on monogenic autoinflammatory diseases such as SAVI .
    diABZI-i
  • HY-178049A
    UM-259 hydrochloride

    		STING Cardiovascular Disease
    UM-259 hydrochloride is a STING inhibitor with activity against both murine and human STING (including the STING R232 mutant). UM-259 hydrochloride inhibits STING-dependent signaling pathways, blocks STING oligomerization, and acts on human primary CD14 + monocytes. UM-259 hydrochloride can be used for research on amyotrophic lateral sclerosis, lupus erythematosus, Aicardi-Goutières syndrome, and infant-onset STING-associated vasculopathy .
    UM-259 hydrochloride

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