1 Result for "

SW208108

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SW208108" in MCE Product Catalog:

Cat. No.: HY-114606
CAS No.: 1673557-43-1
Research Areas:  

Cancer

SW208108 is a prodrug of dMe-SW208108, a CYP4F11-activated SCD inhibitor, with an IC50 value of 9 nM. SW208108 undergoes demethylation by CYP4F11 to form the active metabolite dMe-SW208108, thereby inhibiting enzyme function. SW208108 depletes unsaturated fatty acids, induces cytotoxicity in non-small cell lung cancer (NSCLC) cells expressing CYP4F11, and does not affect SCD activity in mouse sebocytes. SW208108 can be used in studies related to NSCLC .
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