7 Results for "

Sigmar1

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Sigmar1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0837
CAS No.: 60-70-8
Synonyms: NSC17821; NSC23880
Veratramine (NSC17821; NSC23880) is an orally active inhibitor of the PI3K/Akt/mTOR signaling pathway and a SIGMAR1 modulator. Veratramine induces autophagic apoptosis of tumor cells, arrests the cell cycle at the G0/G1 phase, and inhibits epithelial-mesenchymal transition (EMT)-related proteins to reduce tumor migration. Veratramine reduces spinal cord and sciatic nerve pathological damage in a neuropathy model by inhibiting SIGMAR1 binding to NMDAR and phosphorylation of NMDAR Ser896. Veratramine has anti-tumor proliferation, apoptosis induction, anti-inflammatory and neuroprotective activities, and can be used in the study of cancers such as liver cancer and osteosarcoma, as well as diabetic peripheral neuropathy [1] .
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Cat. No.: HY-RS12909
Research Areas:  

Others

Sigmar1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sigmar1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS12908
Research Areas:  

Others

SIGMAR1 Human Pre-designed siRNA Set A contains three designed siRNAs for SIGMAR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS12910
Research Areas:  

Others

Sigmar1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sigmar1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N0837R
CAS No.: 60-70-8
Synonyms: NSC17821 (Standard); NSC23880 (Standard)
Veratramine (NSC17821; NSC23880) (Standard) is the analytical standard of Veratramine (HY-N0837). This product is intended for research and analytical applications. Veratramine (NSC17821; NSC23880) is an orally active inhibitor of the PI3K/Akt/mTOR signaling pathway and a SIGMAR1 modulator. Veratramine induces autophagic apoptosis of tumor cells, arrests the cell cycle at the G0/G1 phase, and inhibits epithelial-mesenchymal transition (EMT)-related proteins to reduce tumor migration. Veratramine reduces spinal cord and sciatic nerve pathological damage in a neuropathy model by inhibiting SIGMAR1 binding to NMDAR and phosphorylation of NMDAR Ser896. Veratramine has anti-tumor proliferation, apoptosis induction, anti-inflammatory and neuroprotective activities, and can be used in the study of cancers such as liver cancer and osteosarcoma, as well as diabetic peripheral neuropathy [1] .
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Cat. No.: HY-P811656
Synonyms: OPRS1, SRBP, AAG8, Sigmar1, Sigma non-opioid intracellular receptor 1, Aging-associated gene 8 protein, SR31747-binding protein, Sigma 1-type opioid receptor, SR-BP, SIG-1R, Sigma1-receptor, Sigma1R, hSigmar1

Host:  

Rabbit

Application:  

WB, IF-Tissue, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P703280
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Sigmar1; SR-BP; Prev. OPRS1; SR31747 Binding Protein 1; Sigma 1-Type Opioid Receptor; Opioid Receptor, Sigma 1; SR-BP1; SR31747-Binding Protein; Aging-Associated Gene 8 Protein; Sigma1-Receptor; HSigmar1; ALS16; Sigma1R; DSMA2; SIG-1R; HMNR2; Sigma Non-Op
Species:  
Human
Source:  
Sf9 insect cells
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