6 Results for "

Sonidegib

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Sonidegib" in MCE Product Catalog:

13
13 Cited Publications
Cat. No.: HY-16582A
CAS No.: 956697-53-3
Synonyms: Erismodegib; LDE225; NVP-LDE225
Target:  

Smo

Research Areas:  

Cancer

Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .
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13
13 Cited Publications
Cat. No.: HY-16582
CAS No.: 1218778-77-8
Synonyms: Erismodegib diphosphate; LDE225 diphosphate; NVP-LDE225 diphosphate
Target:  

Smo

Research Areas:  

Cancer

Sonidegib diphosphate (Erismodegib diphosphate) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .
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Cat. No.: HY-117229
CAS No.: 1221722-10-6
Purity:  ≥98.0%
Target:  

Drug Metabolite

Research Areas:  

Cancer

Sonidegib metabolite M48 is the main circulating metabolite of Sonidegib. Sonidegib is a hedgehog pathway inhibitor. M48 showed a much longer Tmax (60 h) than Sonidegib .
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Cat. No.: HY-16582AR
CAS No.: 956697-53-3
Synonyms: Erismodegib (Standard); LDE225 (Standard); NVP-LDE225 (Standard)
Target:  

Smo Reference Standards

Research Areas:  

Cancer

Sonidegib (Standard) is the analytical standard of Sonidegib. This product is intended for research and analytical applications. Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .
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Cat. No.: HY-157571S
N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8 is a stable isotope of hydrazine impurities in Sonidegib (HY-16582A).
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Cat. No.: HY-16582AS
Synonyms: Erismodegib-d4; LDE225-d4; NVP-LDE225-d4
Sonidegib-d4 is a isotope of Sonidegib. Sonidegib is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .
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