956697-53-3
956697-53-3
Chemical Structure
Sonidegib
Synonym(s): Erismodegib; LDE225; NVP-LDE225
- CAS No.: 956697-53-3
- Formula:C26H26F3N3O3
- Molecular Weight:485.50
IUPAC Name: N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide
InChIKey: VZZJRYRQSPEMTK-CALCHBBNSA-N
SMILES: O=C(C1=C(C)C(C(C=C2)=CC=C2OC(F)(F)F)=CC=C1)NC3=CC=C(N=C3)N4C[C@@H](C)O[C@@H](C)C4
Biological Activity: Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sonidegib | 99.98% | Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively. | ||||||||||||||||||||
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Sonidegib (Standard) | ≥98% | Sonidegib (Standard) is the analytical standard of Sonidegib. This product is intended for research and analytical applications. Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively. | ||||||||||||||||||||
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Sonidegib-d4 | Sonidegib-d4 is a isotope of Sonidegib. Sonidegib is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively. | |||||||||||||||||||||
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References
