14 Results for "

Staphylococcal protein A

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Staphylococcal protein A" in MCE Product Catalog:

15
15 Publications Verification
Cat. No.: HY-B1455
CAS No.: 18323-44-9
Research Areas:  

Infection Cancer

Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .
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3
3 Cited Publications
Cat. No.: HY-107193
CAS No.: 1405-87-4
Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor .
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Cat. No.: HY-P99770
CAS No.: 2241724-48-9
Synonyms: 514-G3

Target:  

Bacterial

Research Areas:  

Infection

Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection .
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Cat. No.: HY-N7118
CAS No.: 58207-19-5
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Cancer

Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla) .
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Cat. No.: HY-B1455S1
CAS No.: 2140264-63-5
Clindamycin- 13C,d3 is the 13C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .
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Cat. No.: HY-118917
CAS No.: 297730-05-3
Target:  

IMPDH

Research Areas:  

Inflammation/Immunology

VX-148 is an orally active immunosuppressant, which is a non-competitive inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor with Ki values for IMPDH Ⅱ and IMPDH Ⅰ of 6 and 14 nM respectively. VX-148 can significantly inhibit the proliferation of human peripheral blood mononuclear cells (PBMC) stimulated by T-cell mitogen (PHA) or B-cell mitogen (SPAS). VX-148 has high selectivity for lymphocytes (such as L1210, Jurkat T cells, and Raji B cells), but has no significant toxicity to non-lymphoid cells. VX-148 can inhibit antibody responses in mouse models and significantly prolong the survival time of transplanted skin in allogeneic skin transplantation models. VX-148 can be used in the research of autoimmune diseases (such as rheumatoid arthritis, psoriasis) and organ transplantation anti-rejection .
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Cat. No.: HY-146330
CAS No.: 2249757-45-5
Target:  

Bacterial

Research Areas:  

Infection

FtsZ-IN-2 (Compound 19) is an inhibitor of the bacterial cell division protein FtsZ with GTPase inhibitory activity. FtsZ-IN-2 exhibits anti-staphylococcal activity with MIC values of 2 µg/ml for MSSA and MRSA .
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Cat. No.: HY-101829
CAS No.: 116-42-7
Purity:  99.37%
Synonyms: Sulfaproxylin; Sulfaproxyline
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Sulfaproxyline (Sulfaproxylin; Sulfaproxyline) is a sulfonamide antibiotic that inhibits bacterial dihydropteroate synthase, thereby blocking folate biosynthesis required for nucleic acid production. Sulfaproxyline shows antimicrobial activity primarily against Staphylococcus species and common uropathogens. Sulfaproxyline reduces bacterial growth by impairing DNA and protein synthesis. Sulfaproxyline can be used for research of staphylococcal and urinary tract infections .
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Cat. No.: HY-B1455S
CAS No.: 1356933-72-6
Clindamycin-d3 (hydrochloride) is the deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .
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Cat. No.: HY-N7118R
CAS No.: 58207-19-5
Research Areas:  

Infection Cancer

Clindamycin (hydrochloride monohydrate) (Standard) is the analytical standard of Clindamycin (hydrochloride monohydrate). This product is intended for research and analytical applications. Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla) .
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Cat. No.: HY-B1455R
CAS No.: 18323-44-9
Clindamycin (Standard) is the analytical standard of Clindamycin. This product is intended for research and analytical applications. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .
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Cat. No.: HY-P700320
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Immunoglobulin G-binding protein A; IgG-binding protein A; Staphylococcal protein A; spa; SAOUHSC_00069
Species:  
Staphylococcus aureus
Source:  
E. coli
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Cat. No.: HY-P700331A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Immunoglobulin G-binding protein A; IgG-binding protein A; Staphylococcal protein A; spa; SAOUHSC_00069; Immunoglobulin G-binding protein G; spg; IgG-binding protein G
Species:  
Staphylococcus aureus
Source:  
E. coli
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Cat. No.: HY-P11905
CAS No.: 874909-17-8
Research Areas:  

Others

FcIII peptide is a 13-amino-acid peptide that competitively binds the hinge region of IgG Fc fragment with high affinity. FcIII peptide has an inhibition constant Ki of 25 nM when competing with Protein A for binding sites. FcIII peptide displays high selectivity toward human IgG subtypes yet weak binding affinity for murine IgG1. FcIII peptide anchors IgG Fc through hydrophobic interactions formed by tryptophan and valine residues, alongside multiple hydrogen bonds and salt bridges. FcIII peptide alters the local microenvironment of conjugated fluorescein after binding IgG Fc, which triggers enhanced fluorescent signals. FcIII peptide can be applied to researches related to monoclonal antibody production. .
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