2. Anti-infection
  3. Bacterial
  4. Omodenbamab

Omodenbamab  (Synonyms: 514-G3)

Cat. No.: HY-P99770 Purity: 96.77%
COA

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Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection.

For research use only. We do not sell to patients.

Omodenbamab Chemical Structure

Omodenbamab Chemical Structure

CAS No. : 2241724-48-9

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5 mg USD 780 In-stock
10 mg USD 1250 In-stock
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Omodenbamab Related Antibodies

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Description

Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection[1].

In Vitro

Omodenbamab (514-G3) binds to S. aureus and leaves the Fc region exposed for FcγR1A receptor binding[1]. Omodenbamab (10 μg/mL; 30 min, 1.5 hr, and 2.5 hr) supports the opsonophagocytic killing of S. aureus by human blood cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Omodenbamab Related Antibodies
In Vivo

Omodenbamab (514-G3; 2.5 mg/mice and 10 mg/mice; i.v.) protects mice against lethal challenge with MRSA in a bacteremia model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Balb/C mice with MRSA in a bacteremia model[1]
Dosage: 2.5 mg/mice and 10 mg/mice
Administration: Intravenous injection
Result: Increased mouse Balb/C mice with MRSA in a bacteremia model survival.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Omodenbamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 96.77%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Omodenbamab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Omodenbamab2241724-48-9514-G3BacterialS. aureusStaphylococcal protein Abloodstream infectionInhibitorinhibitorinhibit

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