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Synthetic peptides

" in MedChemExpress (MCE) Product Catalog:

169

Inhibitors & Agonists

2

Screening Libraries

1

Fluorescent Dyes

2

Biochemical Assay Reagents

169

Peptides

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P0202
    Endothelin 1 (swine, human)
    Maximum Cited Publications
    8 Publications Verification

    ET-1 (swine, human)

    Endothelin Receptor Metabolic Disease Inflammation/Immunology
    Endothelin 1 (swine, human) (ET-1) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
    Endothelin 1 (swine, human)
  • HY-139201A

    PDLHB (MW 70000-150000)

    Biochemical Assay Reagents CaSR Neurological Disease Cancer
    Poly-D-lysine hydrobromide (MW 70000-150000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
    Poly-D-lysine hydrobromide (MW 70000-150000)
  • HY-P0267
    Melanotan (MT)-II
    1 Publications Verification

    Melanocortin Receptor Neurological Disease
    Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.
    Melanotan (MT)-II
  • HY-P0139
    Gap 27
    5+ Cited Publications

    Gap Junction Protein Cardiovascular Disease
    Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment .
    Gap 27
  • HY-139201

    PDLHB (MW 30000-70000)

    CaSR Neurological Disease Metabolic Disease Cancer
    Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
    Poly-D-lysine hydrobromide (MW 30000-70000)
  • HY-P0290
    GRGDSP
    5 Publications Verification

    Integrin Cancer
    GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
    GRGDSP
  • HY-P1034
    DAPTA
    4 Publications Verification

    D-Ala-peptide T-amide; Adaptavir

    CCR HIV Infection Endocrinology
    DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5, and shows potent anti-HIV activities.
    DAPTA
  • HY-P1146
    Semax
    1 Publications Verification

    Amyloid-β Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Semax is a BBB-penetrable adrenocorticotropic hormone-like peptide and can form stable complexes with Cu 2+. Semax is a synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10). Semax has immunomodulatory, nootropic and neuroprotective activities. Semax can be used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia .
    Semax
  • HY-P1714

    FE 203799

    GLP Receptor Metabolic Disease
    Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
    Apraglutide
  • HY-P1626

    Opioid Receptor Neurological Disease
    Acetyl tetrapeptide-15 is a synthetic peptide. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway. Acetyl tetrapeptide-15 is used in the cosmetics for sensitive skin .
    Acetyl tetrapeptide-15
  • HY-114426A

    Gap Junction Protein Metabolic Disease
    AT-1002 TFA, a 6-mer synthetic peptide , is a tight junction regulator and absorption enhancer .
    AT-1002 TFA
  • HY-139201B

    PDLHB (MW 84000)

    CaSR Neurological Disease Cancer
    Poly-D-lysine hydrobromide (MW 84000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .
    Poly-D-lysine hydrobromide (MW 84000)
  • HY-P6028A

    N-myristoyltransferase Others
    GSNKSKPK-NH2 TFA is a synthetic model peptide based on the c-Src N-terminal sequence and model peptide substrate for human NMT1 and NMT2.GSNKSKPK-NH2 TFA facilitates in vitro assays measuring transfer of myristate or X10 fatty acid moieties .
    GSNKSKPK-NH2 TFA
  • HY-P0222
    PKI(5-24)
    3 Publications Verification

    PKA Others
    PKI(5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM. PKI(5-24) corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor .
    PKI(5-24)
  • HY-P1701

    Opioid Receptor Cardiovascular Disease Neurological Disease
    Morphiceptin is a potent and specific agonist for morphine (μ) receptors. Morphiceptin, as a synthetic peptide, is the amide of a fragment of the milk protein β-casein. Morphiceptin has morphinelike activities and is highly specific for morphine (μ) receptors but not for Enkephalin receptors .
    Morphiceptin
  • HY-P1000

    SFLLRNPNDKYEPF

    Thrombin Cardiovascular Disease
    TRAP-14 (SFLLRNPNDKYEPF) is a synthetic thrombin receptor agonist peptide.
    TRAP-14
  • HY-137199

    Biochemical Assay Reagents Others
    Pro-Phe-Arg-AMC is a synthetic peptide substrate of Cysteine peptidases (CPs) .
    Pro-Phe-Arg-AMC
  • HY-P1155
    GRF (1-29) amide (rat)
    1 Publications Verification

    rGHRH(1-29)NH2

    GHSR Cancer
    GRF (1-29) amide (rat) is a synthetic peptide which can stimulate the growth hormone (GH) secretion.
    GRF (1-29) amide (rat)
  • HY-P0312
    c-Myc Peptide TFA
    1 Publications Verification

    c-Myc Cancer
    c-Myc Peptide (TFA) is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein, and participates in regulation of growth-related gene transcription.
    c-Myc Peptide TFA
  • HY-P10551

    Transmembrane Glycoprotein NF-κB TNF Receptor Cardiovascular Disease
    ApoA-I mimetic peptide 5A is a synthetic peptide molecule designed based on the structure and function of naturally occurring apolipoprotein A-I (Apo A-I). ApoA-I mimetic peptide 5A can promote the efflux of cholesterol from cells and help reduce the accumulation of cholesterol in cells. ApoA-I mimetic peptide 5A also shows anti-inflammatory activity and can reduce inflammatory markers in blood and tissues. ApoA-I mimetic peptide 5A can be used in the study of cardiovascular diseases .
    ApoA-I mimetic peptide 5A
  • HY-P1146A
    Semax acetate
    1 Publications Verification

    Amyloid-β Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Semax acetate is a BBB-penetrable adrenocorticotropic hormone-like peptide and can form stable complexes with Cu 2+. Semax acetate is a synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10). Semax acetate has immunomodulatory, nootropic and neuroprotective activities. Semax acetate can be used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia .
    Semax acetate
  • HY-P1595

    PKA PKC Metabolic Disease
    CREBtide is a CREB (cAMP response element binding protein)-like peptide. CREBtide, a synthetic 13 amino acid peptide, has been reported as a PKA and PKC substrate.
    CREBtide
  • HY-P2207

    Biochemical Assay Reagents Others
    Sinapultide is a 21-amino-acid peptide that mimics the action of human surfactant protein-B (SP-B). Sinapultide can be used for synthetic phospholipids surfactants improvement .
    Sinapultide
  • HY-P4896

    Integrin Cancer
    FITC-Ahx Gly Arg Gly Asp Ser Pro is a GRGDSP (HY-P0290) coupled to FITC. GRGDSP is an integrin inhibitor that can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis .
    FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro
  • HY-P0202A
    Endothelin 1 (swine, human) TFA
    Maximum Cited Publications
    8 Publications Verification

    ET-1 (swine, human) TFA

    Endothelin Receptor Cardiovascular Disease
    Endothelin 1 (swine, human) (ET-1) TFA is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 TFA acts through two types of receptors ETA and ETB .
    Endothelin 1 (swine, human) TFA
  • HY-105077A

    INN 00835 diTFA

    5-HT Receptor Neurological Disease
    Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action . Nemifitide diTFA is a peptide analog of melanocyte-inhibiting factor (MIF) . Nemifitide diTFA can cross the blood-brain barrier .
    Nemifitide diTFA
  • HY-P3601

    FGF basic (1-24)

    Bacterial HBV Infection Inflammation/Immunology
    Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research .
    Brain Derived Basic Fibroblast Growth Factor (1-24)
  • HY-W098322

    Drug Intermediate Others
    Z-Lys-OMe hydrochloride is a synthetic intermediate that can be used in the synthesis of peptide enzyme substrates and lysine cationic surfactants.
    Z-Lys-OMe hydrochloride
  • HY-19529

    Endothelin Receptor Cardiovascular Disease Endocrinology
    Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM.
    Ro 46-2005
  • HY-P1930A

    Integrin Inflammation/Immunology
    Risuteganib hydrochloride is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide. Risuteganib hydrochloride is an anti-integrin that downregulates oxidative stress and restores homeostasis, and targets three integrin receptors that are implicated in dry age-related macular degeneration (AMD) in order to restore homeostasis in the retina .
    Risuteganib hydrochloride
  • HY-139201C

    PDLHB (MW 1000-5000)

    CaSR Others
    Poly-D-lysine hydrobromide (MW 1000-5000) (PDLHB (MW 1000-5000)) is a synthetic cationic polypeptide polymer commonly used as a cell adhesion promoter and surface coating molecule. Poly-D-lysine hydrobromide is also known as a calcium-sensing receptor (CaSR) agonist peptide .
    Poly-D-lysine hydrobromide (MW 1000-5000)
  • HY-P3942

    Adhesion G Protein-coupled Receptors (AGPCRs) Others
    SDP116 is a synthetic Stachel-derived peptide of GPR116 Stachel peptide. SDP116 has ADGRF5 agonist effect .
    SDP116
  • HY-P2496

    Endothelin Receptor Cardiovascular Disease
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled
  • HY-P4336

    Carboxypeptidase Others
    Dansyl-Ala-Arg is a synthetic peptide. Dansyl-Ala-Arg can be used for various biochemical studies .
    Dansyl-Ala-Arg
  • HY-114426

    Gap Junction Protein Metabolic Disease
    AT-1002, a 6-mer synthetic peptide , is a tight junction regulator and absorption enhancer .
    AT-1002
  • HY-P5486

    Bacterial Others
    Tet-20 is a biological active peptide. (Tet-20, is a synthetic cathelicidin-derived peptide. It was tested as infection-resistant coating for medical devices. When tethered on an implant surface Tet-20 exhibited broad antimicrobial activities both in vivo and in vitro. It can stop biofilm formation and appears to be non-toxic to eukaryotic cells)
    Tet-20
  • HY-P10529

    Trk Receptor Infection
    Ganglioside GM1-binding peptide p3 is a synthetic peptide that can specifically bind to the pentasaccharide part of GM1 ganglioside. The dynamic transformation of Ganglioside GM1-binding peptide p3 may play an important role in the function of GM1 as a multiple receptor, such as in the classical pathway of cholera toxin infection. Ganglioside GM1-binding peptide p3 can be used to study the interaction between GM1 and its ligands .
    Ganglioside GM1-binding peptide p3
  • HY-P1344A

    DAPK Cancer
    DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a Km of 9 μM .
    DAPK Substrate Peptide TFA
  • HY-P5884A

    PKC Others
    PKCθ pseudosubstrate peptide inhibitor, myristoylated TFA is a synthetic peptide that can be used to study the mechanism of action of PKCθ .
    PKCθ pseudosubstrate peptide inhibitor,myristoylated TFA
  • HY-149988

    MDM-2/p53 Cancer
    UNP-6457 is a potent active MDM2-p53 interaction inhibitor with an IC50 values of 8.9 nM .
    UNP-6457
  • HY-W003592A

    Drug Intermediate Others
    L-Orinithine lactam hydrochloride is a synthetic intermediate. L-Orinithine lactam (hydrochloride) can be used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides .
    L-Orinithine lactam hydrochloride
  • HY-P6028

    N-myristoyltransferase Others
    GSNKSKPK-NH2 is a synthetic model peptide based on the c-Src N-terminal sequence and model peptide substrate for human NMT1 and NMT2.GSNKSKPK-NH2 facilitates in vitro assays measuring transfer of myristate or X10 fatty acid moieties .
    GSNKSKPK-NH2
  • HY-P5309

    Biochemical Assay Reagents Inflammation/Immunology
    IgA1 Peptide GN5 is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .
    IgA1 Peptide GN5
  • HY-138143

    Chromozym-TH

    Fluorescent Dye Others
    N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V) .
    N-(p-Tosyl)-GPR-pNA acetate
  • HY-P1714A

    FE 203799 TFA

    GLP Receptor Metabolic Disease
    Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
    Apraglutide TFA
  • HY-P3912A

    Interleukin Related Infection
    Endotoxin inhibitor TFA is a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor TFA inhibits the febrile response to LPS with very low toxicity and lethality .
    Endotoxin inhibitor TFA
  • HY-P10462

    Synthetic anti-inflammatory peptide 15

    HDAC NF-κB Inflammation/Immunology
    SAP15 (Synthetic anti-inflammatory peptide 15) is a synthetic anti-inflammatory peptide consisting of 15 amino acids designed from human beta-defensin 3. SAP15 has the ability to penetrate cells and is able to induce downregulation of intracellular inflammation. SAP15 inhibits inflammation by inhibiting the phosphorylation of HDAC5 and thereby reducing the phosphorylation of NF-κB p65. SAP15 inhibits HDAC5 and NF-κB p65 phosphorylation in LPS (HY-D1056)-induced macrophages. SAP15 increases the expression of aggrecan and type II collagen and decreases the expression of osteocalcin in LPS-induced chondrocytes. SAP15 can be used in the study of inflammation regulation and anti-inflammatory therapy of biomaterials .
    SAP15
  • HY-P2641

    MMP Cancer
    Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro .
    Peptide 74
  • HY-P4111A

    CXCR Cancer
    Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. Peptide R (TFA) shows outstanding capacities to remodel the tumor stroma. Peptide R (TFA) can be used for solid tumor (glioblastoma, etc.) research .
    Peptide R TFA
  • HY-P3523

    Integrin Others
    KGDS is synthetic peptides, targeting integrin GPIIb-IIIa located on the membrane of human activated platelets. Amino acid sequence: Lys-Gly-Asp-Ser .
    KGDS

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