2 Results for "

T cell repertoire

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "T cell repertoire" in MCE Product Catalog:

Cat. No.: HY-P990762
CAS No.: 2484772-72-5
Synonyms: BCD-180

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Seniprutug (BCD-180) is a humanized monoclonal antibody targeting the TRBV9 fragment. Seniprutug induces antibody-dependent cell-mediated cytotoxicity to eliminate TRBV9 + T cells. Seniprutug is applicable to research related to active radiographic axial spondyloarthritis .
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Cat. No.: HY-184499
CAS No.: 2420554-24-9
Target:  

MHC Aminopeptidase

Research Areas:  

Cancer

GRWD5769 is an orally potent ERAP1 inhibitor. GRWD5769 regulates the peptide repertoire presented by MHC-I, alters TCR diversity/clonality, reprograms antigen-experienced T cells, induces novel T cell responses, drives tumor cell killing, and alleviates T cell exhaustion. GRWD5769 can be used in the research of advanced solid malignancies, microsatellite-stable colorectal cancer, non-small cell lung cancer, bladder cancer, hepatocellular carcinoma, head and neck squamous cell carcinoma, and cervical cancer .
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