1 Result for "

TFAP4/Wnt/

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TFAP4/Wnt/" in MCE Product Catalog:

Cat. No.: HY-173482
CAS No.: 3115114-11-6
Target:  

Wnt β-catenin

Research Areas:  

Cancer

TFAP4/Wnt/β-catenin-IN-1 (Compound A61) is an orally active TFAP4/Wnt/β-catenin inhibitor. TFAP4/Wnt/β-catenin-IN-1 has significant anticancer activity against a variety of cancer cells (such as gastric cancer, lung cancer, breast cancer, etc.), and has the strongest anticancer activity against MGC-803 gastric cancer cells (IC50: 3.92 μM). TFAP4/Wnt/β-catenin-IN-1 induces apoptosis and cell cycle arrest (S phase) in cancer cells by inhibiting the TFAP4/Wnt/β-catenin signaling pathway. TFAP4/Wnt/β-catenin-IN-1 can be used in the study of gastric cancer .
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