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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
TGF-β receptor 2
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "TGF-β receptor 2" in MCE Product Catalog:
3
3 Cited Publications
Research Areas:
ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 hydrochloride reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-β1/Smad signaling. ENMD-1068 hydrochloride also inhibits the proliferation of endometrial cells and induces apoptosis of epithelial cells in the lesion. ENMD-1068 hydrochloride can be used in the study of endometriosis and liver fibrosis .
Target:
Research Areas:
Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury .
Cat. No.: HY-124748
CAS No.: 789488-77-3
Research Areas:
ENMD-1068 is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-β1/Smad signaling. ENMD-1068 also inhibits the proliferation of endometrial cells and induces apoptosis of epithelial cells in the lesion. ENMD-1068 can be used in the study of endometriosis and liver fibrosis .
Cat. No.: HY-P73428
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR2; Transforming Growth Factor, Beta receptor II Gamma; Prev. MFS2; Transforming Growth Factor, Beta receptor II Beta; TGF-Beta Type II receptor; Serine/Threonine-Protein Kinase receptor; TGF-Beta receptor Type-2; receptor Protein Serine/Threonine Kinase; TBR-Ii; TGF-Beta receptor Type IIB; TGFR-2; TGF-Beta receptor Type II; TBRII; TGFbeta-RII; Transforming Growth Factor, Beta receptor II (70/80kDa); LDS1B; Transforming Growth Factor-Beta receptor Type II; LDS2B; Transforming Growth Factor Beta receptor II; TAAD2; TbetaR-II; AAT3; Transforming Growth Factor, Beta receptor II Epsilon; FAA3; Transforming Growth Factor, Beta receptor II Alpha; LDS2; Transforming Growth Factor, Beta receptor II Delta; RIIC; Transforming Growth Factor Beta receptor 2; Transforming Growth Factor Beta receptor Type IIC
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-174530
Target:
Research Areas:
Human TGFBR2 mRNA encodes the human transforming growth factor beta receptor 2 (TGFBR2) protein, a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. TGFBR2/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis.
Cat. No.: HY-P992076
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
