2 Results for "

TNBC patient-derived organoids

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "TNBC patient-derived organoids" in MCE Product Catalog:

Cat. No.: HY-155246
Target:  

Apoptosis PARP

Research Areas:  

Cancer

PARP1-IN-15 (Compound 6) is a PARP1 inhibitor. PARP1-IN-15 inhibits tankyrase (TNKS) and facilitates DNA double-strand breaks damage. PARP1-IN-15 induces tumor cell apoptosis. PARP1-IN-15 has anti-cancer activity in triple-negative breast cancer (TNBC) cells and TNBC patient-derived organoids. PARP1-IN-15 can be used for research of TNBC with or without BRCA1 mutations .
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Cat. No.: HY-183102
CAS No.: 384860-40-6
Target:  

Aurora Kinase Apoptosis

Research Areas:  

Cancer

ATC12 is a Aurora-A kinase inhibitor. ATC12 binds to Aurora-A and competes with TPX2 for binding to disrupt the Aurora-A/TPX2 interaction. ATC12 inhibits cancer cell proliferation, induces apoptosis and cellular senescence. ATC12 can be used in the research of breast cancer .
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