1 Result for "

TmrB

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TmrB" in MCE Product Catalog:

Cat. No.: HY-N21878
CAS No.: 474328-38-6
Muraymycin D2 is a peptidyl nucleoside natural product derived from Streptomyces spp., possessing competitive translocase I (MraY) inhibitory activity and antibacterial activity. Muraymycin D2 competitively binds to the nucleotide-binding pocket of the MraY substrate via its nucleoside moiety, and upon binding, induces a conformational change in MraY, blocking lipid I synthesis and inhibiting peptidoglycan biosynthesis. Muraymycin D2 exhibits a Ki of 7.6 nM against Bacillus subtilis and an IC50 of 0.39 nM against Staphylococcus aureus. Muraymycin D2 shows antibacterial activity against Escherichia coli and is capable of breaking persistence in chlamydial infection. Muraymycin D2 can be used for research on bacterial infection-related studies, such as chlamydial infection .
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