1 Result for "

VHB937 (IgG1-LALA)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VHB937 (IgG1-LALA)" in MCE Product Catalog:

Cat. No.: HY-P991734A
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

VHB937 (IgG1-LALA) is a derivative of VHB937 (HY-P991734). VHB937 is a human monoclonal antibody that acts as a potent and selective TREM2 agonist. VHB937 enhances the surface expression of TREM2 and its downstream signaling pathways, such as Syk phosphorylation and calcium mobilization. VHB937 has demonstrated significant neuroprotective effects in various animal models of neuroinflammation and neurodegeneration, effectively alleviating pathological damage and reducing pro-inflammatory marker levels. VHB937 can be used in research related to neurodegenerative diseases.
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