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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Vasculogenic mimicry
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Vasculogenic mimicry" in MCE Product Catalog:
Cat. No.: HY-107470
CAS No.: 1256037-58-7
Target:
Research Areas:
Antitumor agent-21 is an aryl-quinolin derivative, with potential anticancer, anti-inflammatory, anti-proliferative, anti-hormonal effects and inhibition of vasculogenic mimicry .
Cat. No.: HY-187373
CAS No.: 1808751-57-6
Target:
Research Areas:
DDAH1-IN-3 is a DDAH1 inhibitor with a human IC50 of 176 μM. DDAH1-IN-3 binds to the DDAH1 active site, forms binding interactions that remodel the binding pocket, and functionally inhibits the enzyme. DDAH1-IN-3 suppresses vasculogenic mimicry in triple-negative breast cancer cells. DDAH1-IN-3 can be used for the research of triple-negative breast cancer .
Cat. No.: HY-183377
CAS No.: 1260071-76-8
Target:
EGFR Akt MMP HIF/HIF Prolyl-Hydroxylase mTOR VEGFR NF-κB Reactive Oxygen Species (ROS) Cadherin
Research Areas:
DMBT is an orally effective anti-tumor metastasis and anti-angiogenesis agent. DMBT downregulates key molecules such as EGFR/p-Akt/HIF-1α/VEGF/MMP-9, inhibits the HIF-1α/VE-cadherin (cadherin)/MMPs and Nrf2/HO-1 signaling pathways, and reduces hypoxia-induced ROS levels as well as the secretion and activity of MMP-9. DMBT inhibits hypoxia-induced vasculogenic mimicry, cancer cell migration, invasion and metastasis, and exhibits no obvious cytotoxicity to normal cells. DMBT reduces the area of laser-induced choroidal neovascularization lesions. DMBT can be used in studies related to breast cancer, melanoma and macular degeneration .
Cat. No.: HY-P992200
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
