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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
WNK2 kinase
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "WNK2 kinase" in MCE Product Catalog:
21
21 Cited Publications
Target:
Research Areas:
WNK463 is an orally bioavailable pan-With-No-Lysine (K) (WNK)-kinase inhibitor with IC50s of 5 nM, 1 nM, 6 nM, and 9 nM for WNK1, WNK2, WNK3, and WNK4, respectively .
Cat. No.: HY-189224
CAS No.: 2728520-90-7
Target:
Research Areas:
WNK2-IN-1 is a WNK2 inhibitor. WNK2-IN-1 inhibits the kinase activity of recombinant WNK2 in a dose-dependent manner, and simultaneously partially inhibits WNK3 and WNK4. WNK2-IN-1 modulates WNK2-SPAK downstream signaling by inhibiting WNK2-mediated SPAK phosphorylation, and further suppresses the proinflammatory transcriptional response induced by IL1β. WNK2-IN-1 can be used in studies related to the WNK2 signaling pathway and osteoarthritis .
Cat. No.: HY-P706115
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: WNK2; WNK Lysine Deficient Protein kinase 2; SDCCAG43; PRKWNK2; Serologically Defined Colon Cancer Antigen 43; NY-CO-43; KIAA1760; Serine/Threonine-Protein kinase WNK2; Protein kinase Lysine-Deficient 2; Protein kinase With No Lysine 2; Antigen NY-CO-43;
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
