1 Result for "

Zanapezil free base

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Zanapezil free base" in MCE Product Catalog:

Cat. No.: HY-19651
CAS No.: 142852-50-4
Synonyms: TAK-147 free base
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Zanapezil (TAK-147) free base is a potent, reversible and selective acetylcholine esterase (AChE) inhibitor. Zanapezil free base shows a potent and reversible inhibition of AChE activity in homogenates of the rat cerebral cortex (IC50=51.2 nM). Zanapezil free base shows a moderate inhibition of muscarinic M1 and M2 receptor binding with Ki values of 234 and 340 nM, respectively. Zanapezil free base can be used for the research of early stages of Alzheimer's disease (AD) .
loading...
    loading...