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Zn

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Amino Acid Derivatives (1) Aminopeptidase (3) Amyloid-β (4) Angiotensin-converting Enzyme (ACE) (1) Annexin A (2) Antibiotic (2) Apoptosis (8) Autophagy (6) Bacterial (8) Beta-lactamase (1) Biochemical Assay Reagents (21) Carbonic Anhydrase (2) Carboxypeptidase (1) CCR (1) CDK (1) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (5) CXCR (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) Drug Derivative (1) Drug Intermediate (1) Drug Metabolite (1) EGFR (2) Endogenous Metabolite (11) Endonuclease (1) Environmental Pollutants (2) ERK (1) Estrogen Receptor/ERR (1) Ferroptosis (1) Fluorescent Dye (17) Fungal (2) GABA Receptor (1) Glycine Receptor (GlyR) (1) GPR39 (5) GSK-3 (1) HDAC (3) Heme Oxygenase (HO) (2) Histamine Receptor (1) HIV (1) HSP (1) IAP (1) iGluR (1) Interleukin Related (1) Isotope-Labeled Compounds (5) Ligands for Target Protein for PROTAC (1) Lipase (1) MDM-2/p53 (1) Mitophagy (1) MMP (2) MOFs (13) Monoamine Oxidase (1) nAChR (1) NF-κB (2) Parasite (1) Prostaglandin Receptor (2) Reactive Oxygen Species (ROS) (7) Reference Standards (8) RNA MTase (1) ROR (1) SARS-CoV (1) SOD (2) STAT (1) Tau Protein (2) TNF Receptor (1) Vasopressin Receptor (1) Wee1 (1)
By Research Areas:	Cancer (30) Cardiovascular Disease (9) Endocrinology (2) Infection (14) Inflammation/Immunology (12) Metabolic Disease (15) Neurological Disease (17)
Click Chemistry:	Alkynes (1)

119

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Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101193

Zinc Protoporphyrin 65+ Cited Publications Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9	Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor. Zinc Protoporphyrin regulates expression of HO-1 at the transcriptional level. The effect of Zinc Protoporphyrin on HO-1 expression is controversial. It was shown to induce HO-1 expression in some cells, but suppress it in others. Zinc Protoporphyrin is used as a screening marker of iron deficiency in vivo. Zinc Protoporphyrin has anti-cancer activity .

HY-10528

Tasquinimod 15+ Cited Publications ABR-215050	HDAC	Cancer
Tasquinimod is an oral antiangiogenic agent, which has the potential for castration-resistant prostate cancer treatment. Tasquinimod binds to the regulatory Zn ²⁺ binding domain of HDAC4 with K_d of 10-30 nM. Tasquinimod also is a S100A9 inhibitor .

HY-101200

Linsidomine hydrochloride SIN-1 chloride	Apoptosis Autophagy Reactive Oxygen Species (ROS) Annexin A NF-κB	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Linsidomine hydrochloride (SIN-1 chloride) is a spontaneous ROS/RNS generator and peroxynitrite donor. Linsidomine hydrochloride is a vasodilator and platelet aggregation inhibitor. Linsidomine hydrochloride induces oxidative stress-induced chondrocyte apoptosis and necrosis. Linsidomine hydrochloride inhibits the migration, proliferation and neointima formation of vascular smooth muscle cells by inhibiting the expression of annexin A2. In addition, low doses of Linsidomine hydrochloride shows protective effects on Zn ²⁺ treated nerve cells .

HY-100202

TPEN 20+ Cited Publications TPEDA	MOFs Reactive Oxygen Species (ROS) Apoptosis Autophagy	Cancer
TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. TPEN has a higher affinity for Zn ²⁺, but a lower affinity for Mg ²⁺ and Ca ²⁺. TPEN induces DNA damage and increases intracellular ROS production. TPEN also inhibits cell proliferation and induces apoptosis .

HY-132295

Azenosertib 4 Publications Verification Zn-c3	Wee1	Cancer
Azenosertib (ZN-c3) is a selective, orally active inhibitor for Wee1 inhibitor (IC₅₀=3.9 nM). Azenosertib exhibits antitumor activity .

HY-Y1878C

Copper sulfate anhydrous, 99% 2 Publications Verification Cupric sulfate anhydrous, 99%	Environmental Pollutants Bacterial	Infection Metabolic Disease
Anhydrous copper sulfate, 99% (Cupric sulfate anhydrous, 99%) is an orally administerable disinfectant. Anhydrous copper sulfate, 99% can be used as a biomaterial or organic compound related to life sciences research, and it can increase the Cu content in rat organs .

HY-14603

Clioquinol 5+ Cited Publications Iodochlorohydroxyquinoline	Environmental Pollutants Antibiotic Autophagy Parasite Fungal Mitophagy	Infection Neurological Disease Inflammation/Immunology Cancer
Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic . Clioquinol is a chelator that binds to Zn ²⁺ and Cu ²⁺ with a greater affinity than it binds to Ca ²⁺ and Mg ²⁺. Clioquinol freely crosses the blood-brain barrier. Clioquinol can be used for the study of Alzheimer's disease .

HY-16074

ATN-224 4 Publications Verification Bischolinetetrathiomolybdate	SOD	Cancer
ATN-224 is an orally active Cu ²⁺/Zn ²⁺-superoxide dismutase 1 (SOD1) inhibitor. ATN-224 inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC₅₀ of 17.5 nM.

HY-137255

Taurolithocholic acid 3-sulfate disodium 3-Sulfotaurolithocholic acid disodium	GPR39	Inflammation/Immunology
Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC₅₀s of 71.6  and 69.4 (absence of Zn ²⁺) and 9 and 9.6 μM (presence of Zn ²⁺) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn ²⁺ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .

HY-119287

TSQ 5 Publications Verification	Fluorescent Dye	Others
TSQ is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λ_max ~470 nm). TSQ can combine with Zn ²⁺ in the presence of Ca ²⁺ and Mg ²⁺ to produce blue fluorescence (Ex/Em = 334/495 nm) .

HY-W127776

Zn(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid zinc disodium tetrahydrate	Biochemical Assay Reagents	Others
Zn(II)-EDTA (Ethylenediaminetetraacetic acid zinc) disodium tetrahydrate is a coordinating agent. Zn(II)-EDTA disodium tetrahydrate coordinates with Zn ²⁺ to modify its solvated structure, provides pre-synthesized EDTA-Zn complexes that release Zn ²⁺ to repair zinc anode defects under interfacial electric field, adsorbs onto zinc anode surface to block oxygen and water molecules, inhibits corrosion and hydrogen evolution reactions, promotes uniform Zn ²⁺ deposition, suppresses zinc dendrite formation, and modulates the hydrogen bonding network within the electrolyte. Zn(II)-EDTA disodium tetrahydrate acts as an electrolyte additive to enhance reversibility and stability of zinc anodes in aqueous zinc-ion batteries .

HY-113238A

Lithocholic acid 3-sulfate disodium Sulfolithocholic acid disodium; LCAS disodium	GPR39 ROR	Metabolic Disease Inflammation/Immunology
Lithocholic acid 3-sulfate disodium is a GPR39 agonist, with EC₅₀ values of 41 μM and 42.4 μM in M39-20 and hGPR39-2 cells, respectively, in the absence of Zn ²⁺, and 0.88 μM and 0.97 μM in the presence of Zn ²⁺. Lithocholic acid 3-sulfate disodium acts as a RORγt ligand. Lithocholic acid 3-sulfate disodium stimulates the GPR39 receptor to initiate intracellular calcium signaling, independent of the Zn ²⁺-binding sites H17 and H19. LCA-3-S selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate disodium can be used in the research of cholestatic liver diseases .

HY-NP009

α-Lactalbumin	Bacterial	Infection Neurological Disease
α-Lactalbumin is a globular whey protein that exists in milk. α-Lactalbumin binds Ca ²⁺, Mg ²⁺, Mn ²⁺, Na ⁺, K ⁺ and Zn ²⁺ ions; among these, Ca ²⁺ binding enhances protein stability, while Zn ²⁺ binding reduces stability and induces aggregation. α-Lactalbumin forms amyloid fibrils, amorphous aggregates, nanoparticles and nanotubes depending on external conditions. α-Lactalbumin exhibits bactericidal and antiviral activities. α-Lactalbumin has anxiolytic and antidepressant activities, and its effects are enhanced under stress conditions .

HY-124171

Zinquin ethyl ester 1 Publications Verification	Fluorescent Dye Drug Derivative	Others
Zinquin ethyl ester is a cell-permeable and lipophilic fluorescent derivative of Zinquin (HY-D0982). Zinquin ethyl ester reacts with protein-bound Zn ²⁺ in cells and forms fluorescent ternary adducts. Zinquin ethyl ester undergoes hydrolysis by intracellular esterases impeding its efflux across the plasma membrane (Ex/Em = 370/470 nm) .

HY-N2362

DL-Alanine DL-2-Aminopropionic acid	Endogenous Metabolite	Metabolic Disease
DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-108699

TM-N1324	GPR39	Neurological Disease Endocrinology
TM-N1324 is an agonist of G-Protein-Coupled Receptor 39 (GPR39) with EC₅₀s of 9 nM/5 nM in the presence of Zn ²⁺, and 280 nM/180 nM in the absence of Zn ²⁺ for human/murine GPR39.

HY-B0600

Tafluprost AFP-168; MK2452	Prostaglandin Receptor	Cardiovascular Disease Others
Tafluprost (AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Tafluprost can inhibit the apoptosis of retinal ganglion cells (RGCs) and rat RGCs cells. Tafluprost promotes axon regeneration by regulating Zn ²⁺-mTORpathway, inhibits intracellular lipid accumulation in human preorbital adipocytes. Tafluprost can be used in the study of optic nerve injury in glaucoma .

HY-W583212

Zn(II) Mesoporphyrin IX ZnMP	Biochemical Assay Reagents Heme Oxygenase (HO)	Inflammation/Immunology
Zn (II) Mesoporphyrin IX (ZnMP) is a heme oxygenase inhibitor with photochemical substrate activity. Zn (II) Mesoporphyrin IX specifically inhibits the activity of bone marrow heme oxygenase. In vitro, Zn (II) Mesoporphyrin IX inhibits the growth of erythroid and myeloid progenitor cells in rabbit bone marrow, and blocks the rhG-CSF-induced mobilization of these progenitor cells into the peripheral blood, exhibiting toxicity to hematopoietic growth and progenitor cell production in rabbits. Zn (II) Mesoporphyrin IX undergoes irreversible photochemical decomposition conforming to first-order kinetic characteristics when irradiated with UV-B in 95% ethanol solution. Zn (II) Mesoporphyrin IX can be used in hematopoietic regulation research, but its photolability and toxic effects on the hematopoietic system require attention .

HY-E70199

Aminopeptidase N (rat) APN/CD13	Aminopeptidase	Cardiovascular Disease
Aminopeptidase N (rat) (APN/CD13) is a Zn ²⁺-dependent membrane-bound exopeptidase that preferentially degrades proteins and peptides with N-terminal neutral amino acids. Aminopeptidase N (rat) is inhibited by angiotensin IV and participates in the regulation of angiotensin IV half-life in the rat striatum .

HY-163428

Perzebertinib Zn-A-1041	EGFR	Inflammation/Immunology Cancer
ZN-A-1041 inhibits HER2 in BT474 cell and wt-EGFR in H838 cells, with IC₅₀s of 9.5 nM and 12 μM respectively. ZN-A-1041 can be used for research of cancer and inflammation .

HY-D0156

ZnAF-1	Fluorescent Dye	Others
ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry .

HY-D0179

Cyclam	Biochemical Assay Reagents	Infection Cardiovascular Disease
Cyclam is a metal chelator that forms metal complexes with a variety of metal ions. Cyclam metal complexes exhibits anti-HIV (such as AMD3100), nitric oxide (NO) releasing and scavenging (such as Zn(II)-Cyclam and Ru(II)-Cyclam), and SOD mimetic (such as Mn(III)-Cyclam and Zn(II)-Cyclam) activities .

HY-D0982

Zinquin	Fluorescent Dye	Others
Zinquin is a cell-impermeant fluorescent sensor and used to observe reactive Zn ²⁺. λex/λem=368/490 nm.

HY-W587430

Glycolithocholic acid 3-sulfate disodium Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium	HIV GPR39	Infection Inflammation/Immunology
Glycolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC₅₀s of 47.9  and 66.8 μM (absence of Zn ²⁺) and 8 and 8.7 μM (presence of Zn ²⁺) in M39-20 and hGPR39-2 cells, respectively. Glycolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn ²⁺ binding sites H17 and H19. Glycolithocholic acid 3-sulfate disodium also inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate disodium can be used for the research of HIV infection and gallbladder disease .

HY-12168

Tanomastat BAY 12-9566	MMP	Cancer
Tanomastat (BAY 12-9566) is an orally bioavailable, non-peptidic biphenyl matrix metalloproteinases (MMPs) inhibitor with a Zn-binding carboxyl group. The K_i values are 11, 143, 301, and 1470 nM for MMP-2, MMP-3, MMP-9, MMP-13 respectively. Tanomastat shows anti-invasive and antimetastatic activity in several experimental tumor models .

HY-158779

Sulfane sulfur probe 4 SSP4	Fluorescent Dye	Others
Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (E_x/E_m=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe ²⁺, Fe ³⁺, Mg ²⁺, Ca ²⁺, and Zn ²⁺) .

HY-E70377

Cu/Zn Superoxide dismutase Cu/Zn SOD	SOD	Inflammation/Immunology Cancer
Cu/Zn Superoxide dismutase (Cu/Zn SOD; SOD1) is a cytosolic copper-zinc dimer form of superoxide dismutase enzyme. Cu/Zn Superoxide dismutase has oxygen radical enzymatic dismutation .

HY-109560

Pentetate zinc trisodium Zn-DTPA trisodium	Biochemical Assay Reagents	Others
Pentetate zinc trisodium (Zn-DTPA trisodium) forms stable chelates with metal ions by exchanging zinc for a metal of greater binding capacity .

HY-21170E

Zinc trifluoromethanesulfonate Zinc(II) Triflate	Biochemical Assay Reagents	Others
Zinc trifluoromethanesulfonate (Zinc (II) Triflate) is a Zn ²⁺ salt commonly used in potentiometric titration to determine the stability constants of Zn ²⁺-quinoline sulfonamide complexes. Aqueous solutions of Zinc trifluoromethanesulfonate form micellar structures, which result in poor desolvation kinetics of Zn ²⁺ and induce dendrite growth on zinc anodes, failing to support long-term cycling of zinc anodes .

HY-101193R

Zinc Protoporphyrin (Standard) Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc Protoporphyrin-9 (Standard)	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-W001939

4-Acetylbenzoic acid	Biochemical Assay Reagents	Cancer
4-Acetylbenzoic acid is a Zn(II) complex. 4-Acetylbenzoic acid is a derivative of benzoic acid that is commonly used in chemical synthesis. 4-Acetylbenzoic acid has an IC₅₀ of 331.3 μM in murine L929 fibroblasts and an IC₅₀ of 176 μM in metastatic melanoma B16 F10 cell lines .

HY-E70565

O-Glycoprotease	Endonuclease	Inflammation/Immunology
O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-type O-glycosylated proteins. O-Glycoprotease sequence is from Akkermansia muciniphila, recombinantly expressed in E.coli, with a 6×His tag at the C-terminus. The enzyme maintains high activity between pH 5.5-7.5 and is resistant to 1M NaCl, but is highly sensitive to EDTA (0.5 mM EDTA) and can be inhibited by Zn ²⁺.

HY-W112937

Zn(II)TMPyP tetrachloride	MOFs	Others
Zn(II)TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0159

ZnAF-1F	Fluorescent Dye	Others
ZnAF-1F is a potent fluorophore for with an K_d value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn ²⁺ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm .

HY-D0159A

ZnAF-1F tetraTFA	Fluorescent Dye	Others
ZnAF-1F tetraTFA is a potent fluorophore for with an K_d value of 2.2 nM. ZnAF-1F tetraTFA can be used as fluorescent probes for Zn ²⁺ in cells. ZnAF-1F tetraTFA shows λ excitation of 489 nm and λ emission of 514 nm .

HY-D0158

ZnAF-2 DA	Biochemical Assay Reagents	Others
ZnAF-2DAavailable for testing Zn(2+)fluorescence, as Zn(2+)Probe (after esterase hydrolysis).

HY-D1894

5-Br-PAPS	Fluorescent Dye	Others
5-Br-PAPS is a highly specific Zn ²⁺ metallochromic indicator. 5-Br-PAPS is used in assays for measuring free Zn ²⁺ by forming a deeply colored red Zn ²⁺ complex .

HY-137159

Bestatin methyl ester	Aminopeptidase Ligands for Target Protein for PROTAC IAP	Cancer
Bestatin methyl ester is a cell permeable Zn2+-binding aminopeptidases inhibitor. Bestatin methyl ester inhibits spore cell differentiation .

HY-DY1055

TSQ (solution)	Fluorescent Dye	Others
TSQ (solution) is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λ_max ~470 nm). TSQ can combine with Zn ²⁺ in the presence of Ca ²⁺ and Mg ²⁺ to produce blue fluorescence (Ex/Em = 334/495 nm) . Solvent and concentration: DMSO: 10 mM

HY-P2516

Tau Peptide (275-305) (Repeat 2 domain)	Tau Protein	Neurological Disease
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's Tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein. Tau Peptide (275-305) specifically coordinates with group IIB metal ions (Zn²⁺, Cd²⁺, Hg²⁺), which can induce their conformational changes and significantly promote their pathological accumulation. Tau Peptide (275-305) can be used to study the role of heavy metals in neurodegenerative diseases .

HY-N2362S2

DL-Alanine-d3 DL-2-Aminopropionic acid-d₃	Endogenous Metabolite	Metabolic Disease
DL-Alanine-d₃ is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-D1264

PMQA Zn-green	Fluorescent Dye	Others
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn ²⁺-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn ²⁺ in living cells .

HY-175260

ZN-c5	Estrogen Receptor/ERR	Cancer
ZN-c5 is a selective and orally active estrogen receptor degrader. ZN-c5 exhibits high potency in the cellular assay (MCF-7, IC₅₀ = 0.3 nM) and binds with high affinity to ERα and ERβ (IC₅₀ = 0.4 nM and 0.8 nM, respectively). ZN-c5 inhibits tumor growth in MCF-7 mouse xenograft model and WHIM20 xenograft model. ZN-c5 can be used for the study of breast cancer .

HY-W583271

Zn(II) Deuteroporphyrin IX 2,4 bis ethylene glycol	Vasopressin Receptor Biochemical Assay Reagents	Metabolic Disease
Zn(II) Deuteroporphyrin IX 2,4 bis ethylene glycol is a heme oxygenase (HO) inhibitor, and inhibiting HO activity can reduce the release of hypothalamic hormones like AVP, OT, and ANP caused by hyperosmolarity. Zn(II) Deuteroporphyrin IX 2,4 bis ethylene glycol can be used for research on hyperbilirubinemia .

HY-D0157

ZnAF-2	Biochemical Assay Reagents	Others
ZnAF-2, 6-iso- is a cell-impermeable compound that acts as a high-affinity Zn2 -specific fluorescent probe (Kd = 2.7 nM). It exhibits low basal fluorescence with an approximately 51-fold increase in fluorescence intensity upon stoichiometric (1:1) binding to Zn2 . Little affinity for Ca2 , Mg2 , Na or K .

HY-D1441

Zinquin AM ester	Fluorescent Dye	Others
Zinquin AM ester is an AM ester form of Zinquin. Zinquin, a fluorescent dye, is a commonly used sensor for cellular Zn ²⁺ status .

HY-B1159S

Nitroxoline-d4 8-Hydroxy-5-nitroquinoline-d₄; 5-Nitro-8-quinolinol-d₄	Bacterial Autophagy Antibiotic	Infection Cancer
Nitroxoline-d₄ is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe ²⁺ and Zn ²⁺ ions from the biofilm matrix .

HY-153141

MP-1	RNA MTase	Cancer
MP-1 is a potent Fumarate hydratase-dependent hit. MP-1 engages an array of functional cysteines, including one lying in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1. MP-1 causes fumarate hydratase-dependent synthetic lethality in a metastatic hereditary leiomyomatosis and renal cell carcinoma cell line .

HY-W585934

Fructose-phenylalanine Fru-Phe	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Fructose-phenylalanine (Fru-Phe) is a non-competitive angiotensin-converting enzyme (ACE) inhibitor (IC₅₀ =0.19 mM) with antioxidant activities. Fructose-phenylalanine forms a stable complex with Zn ²⁺ ions at the ACE active site, blocking the conversion of angiotensin I to II and thereby lowering blood pressure. Fructose-phenylalanine is promising for research of cardiovascular diseases .

HY-10528S

Tasquinimod-d3 ABR-215050-d₃	HDAC Isotope-Labeled Compounds	Cancer
Tasquinimod-d3 (ABR-215050-d3) is the deuterium labeled Tasquinimod (HY-10528). Tasquinimod is an oral antiangiogenic agent, which plays an important role in castration-resistant prostate cancer. Tasquinimod binds to the regulatory Zn ²⁺ binding domain of HDAC4 with K_d of 10-30 nM. Tasquinimod also is a S100A9 inhibitor .

Cat. No.	Product Name	Type

HY-119287

TSQ 5 Publications Verification	Fluorescent Dye
TSQ is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λ_max ~470 nm). TSQ can combine with Zn ²⁺ in the presence of Ca ²⁺ and Mg ²⁺ to produce blue fluorescence (Ex/Em = 334/495 nm) .

HY-124171

Zinquin ethyl ester 1 Publications Verification	Fluorescent Dye
Zinquin ethyl ester is a cell-permeable and lipophilic fluorescent derivative of Zinquin (HY-D0982). Zinquin ethyl ester reacts with protein-bound Zn ²⁺ in cells and forms fluorescent ternary adducts. Zinquin ethyl ester undergoes hydrolysis by intracellular esterases impeding its efflux across the plasma membrane (Ex/Em = 370/470 nm) .

HY-D0156

ZnAF-1	Fluorescent Dye
ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry .

HY-D0982

Zinquin	Fluorescent Dye
Zinquin is a cell-impermeant fluorescent sensor and used to observe reactive Zn ²⁺. λex/λem=368/490 nm.

HY-158779

Sulfane sulfur probe 4

SSP4

Fluorescent Dye

Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (E_x/E_m=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe ²⁺, Fe ³⁺, Mg ²⁺, Ca ²⁺, and Zn ²⁺) .

HY-D0159

ZnAF-1F	Fluorescent Dye
ZnAF-1F is a potent fluorophore for with an K_d value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn ²⁺ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm .

HY-D0159A

ZnAF-1F tetraTFA	Fluorescent Dye
ZnAF-1F tetraTFA is a potent fluorophore for with an K_d value of 2.2 nM. ZnAF-1F tetraTFA can be used as fluorescent probes for Zn ²⁺ in cells. ZnAF-1F tetraTFA shows λ excitation of 489 nm and λ emission of 514 nm .

HY-D1894

5-Br-PAPS	Fluorescent Dye
5-Br-PAPS is a highly specific Zn ²⁺ metallochromic indicator. 5-Br-PAPS is used in assays for measuring free Zn ²⁺ by forming a deeply colored red Zn ²⁺ complex .

HY-DY1055

TSQ (solution)	Fluorescent Dye
TSQ (solution) is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λ_max ~470 nm). TSQ can combine with Zn ²⁺ in the presence of Ca ²⁺ and Mg ²⁺ to produce blue fluorescence (Ex/Em = 334/495 nm) . Solvent and concentration: DMSO: 10 mM

HY-D1264

PMQA Zn-green	Fluorescent Dye
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn ²⁺-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn ²⁺ in living cells .

HY-136894

Rhod-5N	Fluorescent Dye
Rhod-5N is a cell-impermeant calcium-binding fluorescent dye composed of a BAPTA chelating group and a rhodamine fluorophore. Rhod-5N is often added to MOPS buffer to complex and indicate cation content. The selectivity of Rhod-5N for Cd ²⁺ is higher than other interfering cations ((Na+, K+, Mg ²⁺, Ca ²⁺, Zn ²⁺) except Pb ²⁺), and the detection limit is 3.1 μg/L .

HY-D2958

ZP1BG	Fluorescent Dye
ZP1BG is a SNAP tag fluorescent probe for detecting Zn ²⁺, which is formed by the covalent connection of the zinc sensor ZP1 from the Zinpyr family with the benzyl guanine group. ZP1BG can be used to detect the concentration of Zn ²⁺ in neuronal organelles such as the Golgi apparatus and mitochondria .

HY-DY1083

Zinquin (solution)	Fluorescent Dye
Zinquin (solution) is a cell-impermeant fluorescent sensor and used to observe reactive Zn ²⁺. λex/λem=368/490 nm. Solvent and concentration: DMSO: 5 mM

HY-D3226

Zinc(II) probe-1

Fluorescent Dye

Zinc (II) probe-1 (Compound DNP) is a dual-color Fluorescent probe that can simultaneously monitor Zn ²⁺ and H ⁺. Upon interaction with Zn ²⁺, Zinc (II) probe-1 produces bright blue fluorescence (excitation wavelength: 405 nm; blue channel wavelength: 420-500 nm). Upon interaction with H ⁺, Zinc (II) probe-1 exhibits red fluorescence (excitation wavelength: 561 nm; red channel emission wavelength: 630-730 nm). Zinc (II) probe-1 can be used in studies related to depression .

Cat. No.	Product Name	Type

HY-Y1878C

Copper sulfate anhydrous, 99% 2 Publications Verification Cupric sulfate anhydrous, 99%	Biochemical Assay Reagents
Anhydrous copper sulfate, 99% (Cupric sulfate anhydrous, 99%) is an orally administerable disinfectant. Anhydrous copper sulfate, 99% can be used as a biomaterial or organic compound related to life sciences research, and it can increase the Cu content in rat organs .

HY-137255

Taurolithocholic acid 3-sulfate disodium

3-Sulfotaurolithocholic acid disodium

Biochemical Assay Reagents

Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC₅₀s of 71.6  and 69.4 (absence of Zn ²⁺) and 9 and 9.6 μM (presence of Zn ²⁺) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn ²⁺ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .

HY-W127776

Zn(Ⅱ)-EDTA disodium tetrahydrate

Ethylenediaminetetraacetic acid zinc disodium tetrahydrate

Biochemical Assay Reagents

Zn(II)-EDTA (Ethylenediaminetetraacetic acid zinc) disodium tetrahydrate is a coordinating agent. Zn(II)-EDTA disodium tetrahydrate coordinates with Zn ²⁺ to modify its solvated structure, provides pre-synthesized EDTA-Zn complexes that release Zn ²⁺ to repair zinc anode defects under interfacial electric field, adsorbs onto zinc anode surface to block oxygen and water molecules, inhibits corrosion and hydrogen evolution reactions, promotes uniform Zn ²⁺ deposition, suppresses zinc dendrite formation, and modulates the hydrogen bonding network within the electrolyte. Zn(II)-EDTA disodium tetrahydrate acts as an electrolyte additive to enhance reversibility and stability of zinc anodes in aqueous zinc-ion batteries .

HY-113238A

Lithocholic acid 3-sulfate disodium

Sulfolithocholic acid disodium; LCAS disodium

Biochemical Assay Reagents

Lithocholic acid 3-sulfate disodium is a GPR39 agonist, with EC₅₀ values of 41 μM and 42.4 μM in M39-20 and hGPR39-2 cells, respectively, in the absence of Zn ²⁺, and 0.88 μM and 0.97 μM in the presence of Zn ²⁺. Lithocholic acid 3-sulfate disodium acts as a RORγt ligand. Lithocholic acid 3-sulfate disodium stimulates the GPR39 receptor to initiate intracellular calcium signaling, independent of the Zn ²⁺-binding sites H17 and H19. LCA-3-S selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate disodium can be used in the research of cholestatic liver diseases .

HY-NP009

α-Lactalbumin

Biochemical Assay Reagents

α-Lactalbumin is a globular whey protein that exists in milk. α-Lactalbumin binds Ca ²⁺, Mg ²⁺, Mn ²⁺, Na ⁺, K ⁺ and Zn ²⁺ ions; among these, Ca ²⁺ binding enhances protein stability, while Zn ²⁺ binding reduces stability and induces aggregation. α-Lactalbumin forms amyloid fibrils, amorphous aggregates, nanoparticles and nanotubes depending on external conditions. α-Lactalbumin exhibits bactericidal and antiviral activities. α-Lactalbumin has anxiolytic and antidepressant activities, and its effects are enhanced under stress conditions .

HY-W011060

Cryptand 2.2.2

4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane

Biochemical Assay Reagents

Cryptand 2.2.2 (4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane) is a metal ion chelator. Cryptand 2.2.2 forms stable mononuclear, protonated and dinuclear complexes with copper (II) ions; forms protonated complexes with hydrogen ions; and also forms stable complexes with Zn ²⁺, Co ²⁺, Ni ²⁺, Cd ²⁺, Hg ²⁺ and Pb ²⁺ ions. Cryptand 2.2.2 can be used for the preparation of nanoparticles, transition metal compounds, etc.

HY-W583212

Zn(II) Mesoporphyrin IX

ZnMP

Biochemical Assay Reagents

Zn (II) Mesoporphyrin IX (ZnMP) is a heme oxygenase inhibitor with photochemical substrate activity. Zn (II) Mesoporphyrin IX specifically inhibits the activity of bone marrow heme oxygenase. In vitro, Zn (II) Mesoporphyrin IX inhibits the growth of erythroid and myeloid progenitor cells in rabbit bone marrow, and blocks the rhG-CSF-induced mobilization of these progenitor cells into the peripheral blood, exhibiting toxicity to hematopoietic growth and progenitor cell production in rabbits. Zn (II) Mesoporphyrin IX undergoes irreversible photochemical decomposition conforming to first-order kinetic characteristics when irradiated with UV-B in 95% ethanol solution. Zn (II) Mesoporphyrin IX can be used in hematopoietic regulation research, but its photolability and toxic effects on the hematopoietic system require attention .

HY-Y1890B

Cremophor EL-10

Biochemical Assay Reagents

Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn ²⁺, Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses .

HY-Y0850U5

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Biochemical Assay Reagents

PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu ²⁺, Co ²⁺, Ni ²⁺ and Zn ²⁺ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections .

HY-W001939

4-Acetylbenzoic acid	Biochemical Assay Reagents
4-Acetylbenzoic acid is a Zn(II) complex. 4-Acetylbenzoic acid is a derivative of benzoic acid that is commonly used in chemical synthesis. 4-Acetylbenzoic acid has an IC₅₀ of 331.3 μM in murine L929 fibroblasts and an IC₅₀ of 176 μM in metastatic melanoma B16 F10 cell lines .

HY-W112937

Zn(II)TMPyP tetrachloride	Biochemical Assay Reagents
Zn(II)TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0158

ZnAF-2 DA	Biochemical Assay Reagents
ZnAF-2DAavailable for testing Zn(2+)fluorescence, as Zn(2+)Probe (after esterase hydrolysis).

HY-W583271

Zn(II) Deuteroporphyrin IX 2,4 bis ethylene glycol	Biochemical Assay Reagents
Zn(II) Deuteroporphyrin IX 2,4 bis ethylene glycol is a heme oxygenase (HO) inhibitor, and inhibiting HO activity can reduce the release of hypothalamic hormones like AVP, OT, and ANP caused by hyperosmolarity. Zn(II) Deuteroporphyrin IX 2,4 bis ethylene glycol can be used for research on hyperbilirubinemia .

HY-D0157

ZnAF-2	Biochemical Assay Reagents
ZnAF-2, 6-iso- is a cell-impermeable compound that acts as a high-affinity Zn2 -specific fluorescent probe (Kd = 2.7 nM). It exhibits low basal fluorescence with an approximately 51-fold increase in fluorescence intensity upon stoichiometric (1:1) binding to Zn2 . Little affinity for Ca2 , Mg2 , Na or K .

HY-157917

Nitro-PAPS disodium dihydrate	Biochemical Assay Reagents
Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V .

HY-W001939R

4-Acetylbenzoic acid (Standard)

Biochemical Assay Reagents

4-Acetylbenzoic acid (Standard) is the analytical standard of 4-Acetylbenzoic acid. This product is intended for research and analytical applications. 4-Acetylbenzoic acid is a Zn(II) complex. 4-Acetylbenzoic acid is a derivative of benzoic acid that is commonly used in chemical synthesis. 4-Acetylbenzoic acid has an IC₅₀ of 331.3 μM in murine L929 fibroblasts and an IC₅₀ of 176 μM in metastatic melanoma B16 F10 cell lines .

HY-W011060R

Cryptand 2.2.2 (Standard)

4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane (Standard)

Biochemical Assay Reagents

Cryptand 2.2.2 (Standard) is the analytical standard of Cryptand 2.2.2 (HY-W011060). This product is intended for research and analytical applications. Cryptand 2.2.2 is a metal ion chelating agent that can selectively form complexes with metal ions. At room temperature, Cryptand 2.2.2 can serve as a host molecule, using the chelation effect to selectively bind desired ions (such as Zn ²⁺, Co ²⁺, Ni ²⁺, Cu ²⁺). Cryptand 2.2.2 can be used in the preparation of nanoparticles, transition metal compounds, and so on .

Cat. No.	Product Name	Target	Research Area

HY-P2516

Tau Peptide (275-305) (Repeat 2 domain)	Tau Protein	Neurological Disease
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's Tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein. Tau Peptide (275-305) specifically coordinates with group IIB metal ions (Zn²⁺, Cd²⁺, Hg²⁺), which can induce their conformational changes and significantly promote their pathological accumulation. Tau Peptide (275-305) can be used to study the role of heavy metals in neurodegenerative diseases .

HY-P5700

SAAP Fraction 3	Bacterial	Infection
SAAP Fraction 3 is an antimicrobial peptide. SAAP Fraction 3 is active against P. haemolytica in Zn-saline buffer .

HY-P1285

Conantokin R Con-R	iGluR	Neurological Disease
Conantokin R (Con-R) is an NMDA receptor peptide antagonist with an IC₅₀ of 93 nM. Conantokin R binds Zn ²⁺ and Mg ²⁺ with K_ds of 0.15 μM and 6.5 μM, respectively. Conantokin R shows anticonvulsant activity .

HY-P10627

SOD1 (147-153) human	Amyloid-β	Neurological Disease
SOD1 (147-153) human is a peptide fragment of Cu/Zn superoxide dismutase (SOD1) with a high propensity to form amyloid fibrils. SOD1 (147-153) human may trigger the aggregation of full-length SOD1 and is a common molecular determinant of familial amyotrophic lateral sclerosis (fALS) and sporadic amyotrophic lateral sclerosis (sALS) .

Cat. No.	Product Name

HY-K0256

Chelating Agarose (IDA) 6FF
MCE Chelating Agarose (IDA) 6FF allows flexible chelation with metal ions such as Zn²⁺, Ni²⁺, or Cu²⁺, and is suitable for the purification of His-tagged recombinant proteins expressed in bacterial, mammalian, insect, and baculovirus systems.

HY-K0255

IMAC Agarose (NTA) 6FF

MCE IMAC Agarose (NTA) 6FF is prepared by covalently coupling tetradentate nitrilotriacetic acid (NTA) to an agarose matrix. It features high binding capacity, excellent specificity, and superior ligand stability. The resin allows flexible chelation with metal ions such as Zn²⁺, Ni²⁺, or Cu²⁺, and is suitable for the purification of His-tagged recombinant proteins expressed in bacterial, mammalian, insect, and baculovirus systems.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101193

Zinc Protoporphyrin 65+ Cited Publications Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9	Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification Cancer	Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor. Zinc Protoporphyrin regulates expression of HO-1 at the transcriptional level. The effect of Zinc Protoporphyrin on HO-1 expression is controversial. It was shown to induce HO-1 expression in some cells, but suppress it in others. Zinc Protoporphyrin is used as a screening marker of iron deficiency in vivo. Zinc Protoporphyrin has anti-cancer activity .

HY-N2362

DL-Alanine DL-2-Aminopropionic acid	Human Gut Microbiota Metabolites Classification of Application Fields Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-101193R

Zinc Protoporphyrin (Standard) Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc Protoporphyrin-9 (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis
Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-129200

Aspergillomarasmine A	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite
Aspergillomarasmine A is a natural aminopolycarboxylic acid with potent inhibitory activity against class B metallo-β-lactamases (MBLs). Aspergillomarasmine A inactivates MBLs by removing a catalytic Zn2+ cofactor. Aspergillomarasmine A acts as a selective Zn2+ scavenger, promoting the dissociation of the metal cofactor, thereby indirectly inactivating NDM-1. Aspergillomarasmine A causes the loss of Zn2+ ions from the low-affinity binding site of NDM-1. The action of Aspergillomarasmine A results in the rapid degradation of Zn2+-deficient NDM-1, thereby enhancing its potency as a β-lactam enhancer. The mechanism of Aspergillomarasmine A has broad applicability among different Zn2+ chelators .

HY-P5700

SAAP Fraction 3	Animals Ketones, Aldehydes, Acids Source Classification	Bacterial
SAAP Fraction 3 is an antimicrobial peptide. SAAP Fraction 3 is active against P. haemolytica in Zn-saline buffer .

HY-N15079

Arphamenine B	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial
Arphamenine B is a Zn ²⁺-dependent exopeptidase that selectively removes arginine and/or lysine residues from the NH2-terminus of several peptide substrates. Arphamenine B is an inhibitor of aminopeptidase B that can be isolated from bacteria. Arphamenine B enhances the immune response and is used to characterize novel proteases .

HY-W722245

Pyochelin	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Source Classification	Endogenous Metabolite Bacterial
Pyochelin is a salicylate-based nonribosomal peptide siderophore produced by Pseudomonas aeruginosa. Pyochelin chelates Fe ³⁺ and transports it back into bacterial cells, providing the iron essential for bacterial survival. Pyochelin can also chelate other metals such as Zn ²⁺, Co ²⁺, and Ni ²⁺, which helps bacteria maintain intracellular metal ion homeostasis by chelating and excreting excess metals in response to toxic metal stress. Pyochelin can be used in studies related to Pseudomonas aeruginosa infection .

Species:	Human (4) Mouse (1)
Tag:	His (5)
Source:	HEK293 (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705488

	Azgp1 Protein, Mouse (His) Zn-alpha-2-GP; Zn-alpha-2-glycoprotein; Azgp1	Mouse	E. coli

HY-P70016

	AZGP1 Protein, Human (HEK293, His) 1 Publications Verification rHuZinc-alpha-2-glycoprotein/AZGP1, His; Zinc-Alpha-2-Glycoprotein; Zn-Alpha-2-GP; Zn-Alpha-2-Glycoprotein; AZGP1; ZAG; ZnGP1	Human	HEK293
	AZGP1 Proteinas, a key regulator, induces lipid degradation in adipocytes, contributing to fat loss in advanced cancer. Its potential binding to polyunsaturated fatty acids emphasizes its role in lipid metabolism. Interacting with PIP adds complexity to its functional role in cellular processes, highlighting the molecular interplay involved. AZGP1 Protein, Human (HEK293, His) is the recombinant human-derived AZGP1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71048

	SOD1 Protein, Human (His) Superoxide Dismutase [Cu-Zn]; Superoxide Dismutase 1; hSod1; SOD1	Human	E. coli
	SOD1 Protein, an enzyme crucial for cellular defense, operates as a superoxide dismutase, neutralizing radicals to safeguard cells from oxidative stress. Its enzymatic activity underscores the importance of SOD1 in maintaining cellular homeostasis and protecting biological systems from the harmful effects of reactive oxygen species accumulation. SOD1 Protein, Human (His) is the recombinant human-derived SOD1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71048A

	SOD1 Protein, Human (N-His) Superoxide Dismutase [Cu-Zn]; Superoxide Dismutase 1; hSod1; SOD1	Human	E. coli
	SOD1 Protein, an enzyme crucial for cellular defense, operates as a superoxide dismutase, neutralizing radicals to safeguard cells from oxidative stress.Its enzymatic activity underscores the importance of SOD1 in maintaining cellular homeostasis and protecting biological systems from the harmful effects of reactive oxygen species accumulation.SOD1 Protein, Human (N-His) is the recombinant human-derived SOD1 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P703945

	SOD3 Protein, Human (His) SOD 3; SOD3; SODE; Extracellular superoxide dismutase [Cu Zn]; EC SOD; EC-SOD; Extracellular superoxide dismutase [Cu-Zn]; Extracellular superoxide dismutase; Extracellular superoxide dismutase precursor; MGC20077; Superoxide Dismutase 3; Superoxide dismutase 3 extracellular	Human	E. coli
	SOD3 Protein, Human (His) is the recombinant human-derived SOD3 protein, expressed by E. coli, with N-6*His tag.

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Cat. No.	Product Name	Chemical Structure

HY-N2362S2

DL-Alanine-d3

DL-Alanine-d₃ is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-B1159S

Nitroxoline-d4
Nitroxoline-d₄ is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe ²⁺ and Zn ²⁺ ions from the biofilm matrix .

HY-10528S

Tasquinimod-d3
Tasquinimod-d3 (ABR-215050-d3) is the deuterium labeled Tasquinimod (HY-10528). Tasquinimod is an oral antiangiogenic agent, which plays an important role in castration-resistant prostate cancer. Tasquinimod binds to the regulatory Zn ²⁺ binding domain of HDAC4 with K_d of 10-30 nM. Tasquinimod also is a S100A9 inhibitor .

HY-N2362S5

DL-Alanine-15N

DL-Alanine- ¹⁵N is the ¹⁵N labeled DL-Alanine . DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-N2362S

DL-Alanine-13C-1

DL-Alanine- ¹³C-1 is the ¹³C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-N2362S1

DL-Alanine-13C-3

DL-Alanine- ¹³C-3 is the ¹³C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-N2362S8

DL-Alanine-d7

DL-Alanine-d₇ (DL-2-Aminopropionic acid-d₇) is deuterium labeled DL-Alanine. DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-N2362S9

DL-Alanine-13C2,15N

DL-Alanine- ¹³C₂, ¹⁵N (DL-2-Aminopropionic acid- ¹³C₂, ¹⁵N) is ¹³C and ¹⁵N labeled DL-Alanine. DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-W711197

2,2'-Methylene Bis[Ranitidine]-d12
2,2'-Methylene Bis[Ranitidine]-d₁₂ is the deuterium labeled (1Z,4Z)-N1,N5-Bis(2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)-N1,N5-dimethyl-2,4-dinitropenta-1,4-diene-1,1,5,5-tetraamine (Ranitidine Impurity) (HY-Z8387).

Host:	Rabbit (5)
Reactivity:	Human (5) Mouse (4) Rat (3)
Application:	IHC-P (4) ICC/IF (3) IF-Tissue (1) IP (1) IHC-F (1) WB (5) FC (2) ELISA (1)
Isotype:	IgG (5)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (5) Recombinant (4)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82978

	ZNF217 Antibody (YA2723) ZABC1; Zn217; ZnF217	WB	Human
	ZNF217 Antibody (YA2723) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ZNF217.

HY-P85373

	SOD-1 Antibody (YA5065) SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Human, Rat, Mouse
	SOD-1 Antibody (YA5065) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to SOD-1.

HY-P86424

	SOD-1 Antibody (YA6116) SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	SOD-1 Antibody (YA6116) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SOD-1.

HY-P81228

	SOD-1 Antibody (YA3541) ALS antibody; ALS1 antibody; Amyotrophic lateral sclerosis 1 adult antibody; Cu/Zn SOD antibody; Cu/Zn superoxide dismutase antibody; Epididymis secretory protein Li 44 antibody; HEL S 44 antibody; Homodimer antibody; hSod1 antibody; Indophenoloxidase A antibody; IPOA antibody; Mn superoxide dismutase antibody; SOD antibody; SOD soluble antibody; SOD1 antibody; SOD2 antibody; SODC antibody; SODC_HUMAN antibody; Superoxide dismutase [Cu-Zn] antibody; Superoxide dismutase 1 antibody; Superoxide dismutase 1 soluble antibody; Superoxide dismutase Cu Zn antibody; Superoxide dismutase cystolic antibody;	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	SOD-1 Antibody (YA3541) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SOD-1.

HY-P82675

	Superoxide Dismutase 3 Antibody (YA2420) EC SOD; Extracellular superoxide dismutase [Cu Zn]; Extracellular superoxide dismutase precursor; SOD3; Superoxide dismutase 3 extracellular	WB, IHC-P	Human, Mouse
	Superoxide Dismutase 3 Antibody (YA2420) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Superoxide Dismutase 3.

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Cat. No.	Product Name		Classification

HY-180114

NSS-18		Alkynes
NSS-18 is a potent and reversible inhibitor of AChE and MAO-B, with IC₅₀ values of 1.53 and 1.51 μM respectively. NSS-18 can inhibit the self-aggregation of Aβ. NSS-18 inhibits the intracellular generation of ROS induced by Aβ. NSS-18 shows a moderate neuroprotective effect against 6-OHDA (HY-B1081)-induced neurotoxicity. NSS-18 can form chelates with metal ions such as Cu²⁺, Fe³⁺, and Zn²⁺, with the strongest chelation being with Cu²⁺. NSS-18 can be used for the study of Alzheimer's disease .

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